8R62

Solution structure of Risdiplam bound to the RNA duplex formed upon 5'-splice site recognition

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	RNA (5'-R(*AP*UP*AP*CP*(PSU)P*(PSU)P*AP*CP*CP*UP*G)-3')	polymer	11	3428.1	1		Homo sapiens
2	B	RNA (5'-R(P*GP*GP*AP*GP*UP*AP*AP*GP*UP*CP*U)-3')	polymer	11	3547.2	1		Homo sapiens
3	A	7-(4,7-diazaspiro[2.5]octan-7-yl)-2-(2,8-dimethylimidazo[1,2-b]pyridazin-6-yl)-1~{H}-pyrido[1,2-a]pyrimidin-4-one	non-polymer		402.5	1	Chemie (Y59)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	6975.2
Non-Polymers*	Number of molecules	1
	Total formula weight	402.5
All*	Total formula weight	7377.7

*Water molecules are not included.