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8R3Y

Cryo EM structure of a stable LGL/aPKC Iota/Par-6 complex

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(I)
Protein kinase C iota typepolymer33839146.01UniProt (P41743)
Pfam (PF00069)
Pfam (PF00433)
Homo sapiens (human)Atypical protein kinase C-lambda/iota,PRKC-lambda/iota,aPKC-lambda/iota,nPKC-iota
2B
(L)
Lethal(2) giant larvae protein homolog 1polymer937101889.81UniProt (Q15334)
Pfam (PF08366)
Homo sapiens (human)LLGL,DLG4,Hugl-1,Human homolog to the D-lgl gene protein
3C
(P)
Partitioning defective 6 homolog alphapolymer9910856.51UniProt (Q9NPB6)
Pfam (PF00595)
UniProt (by SIFTS) (R4GMM2)
Homo sapiens (human)PAR-6,PAR-6 alpha,PAR-6A,PAR6C,Tax interaction protein 40,TIP-40
4D
(I)
PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTERnon-polymer506.21Chemie (ANP)
Sequence modifications
L: 15 - 951 (UniProt: Q15334)
PDBExternal DatabaseDetails
Gly 148Ser 148conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight151892.3
Non-Polymers*Number of molecules1
Total formula weight506.2
All*Total formula weight152398.5
*Water molecules are not included.

238895

PDB entries from 2025-07-16

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