8R32
Crystal structure of the GluK2 ligand-binding domain in complex with L-glutamate and BPAM344 at 1.60 A resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Glutamate receptor ionotropic, kainate 2 | polymer | 258 | 29242.5 | 2 | UniProt (P42260) Pfam (PF10613) Pfam (PF00060) | Rattus norvegicus (Norway rat) | GluK2,Glutamate receptor 6,GluR-6,GluR6 |
| 2 | C, H (A, B) | GLUTAMIC ACID | non-polymer | 147.1 | 2 | Chemie (GLU) | |||
| 3 | D, I (A, B) | 4-cyclopropyl-7-fluoro-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide | non-polymer | 242.3 | 2 | Chemie (2J9) | |||
| 4 | E, F, J, K (A, B) | CHLORIDE ION | non-polymer | 35.5 | 4 | Chemie (CL) | |||
| 5 | G, L, M (A, B) | SODIUM ION | non-polymer | 23.0 | 3 | Chemie (NA) | |||
| 6 | N, O (A, B) | water | water | 18.0 | 544 | Chemie (HOH) |
Sequence modifications
A, B: 429 - 544 (UniProt: P42260)
A, B: 667 - 805 (UniProt: P42260)
| PDB | External Database | Details |
|---|---|---|
| Gly 428 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 545 | - | linker |
| Thr 546 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 58485.0 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 989.6 | |
| All* | Total formula weight | 59474.6 |
