8R1V

Pseudomonas aeruginosa FabF C164A in complex with N-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-2-(4-methoxyphenoxy)acetamide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	3-oxoacyl-[acyl-carrier-protein] synthase 2	polymer	419	43996.5	2	UniProt (G3XDA2) Pfam (PF00109) Pfam (PF02801) In PDB	Pseudomonas aeruginosa
2	A, B	N-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-2-(4-methoxyphenoxy)acetamide	non-polymer		367.4	2	Chemie (XJR)
3	A, B	DIMETHYL SULFOXIDE	non-polymer		78.1	2	Chemie (DMS)
4	A, B	FORMIC ACID	non-polymer		46.0	7	Chemie (FMT)
5		water	water		18.0	113	Chemie (HOH)

Sequence modifications

A, B: 1 - 414 (UniProt: G3XDA2)

PDB	External Database	Details
Gly -4	-	expression tag
His -3	-	expression tag
Met -2	-	expression tag
Ala -1	-	expression tag
Ser 0	-	expression tag
Ala 164	Cys 164	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	87993.0
Non-Polymers*	Number of molecules	11
	Total formula weight	1213.2
All*	Total formula weight	89206.2

*Water molecules are not included.