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8R1S

Cryo-EM structure of human islet amyloid polypeptide (hIAPP) mutant A25P, polymorph 2

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D, E...
(A, B, C, D, E...)
Islet amyloid polypeptidepolymer383933.310UniProt (P10997)
Pfam (PF00214)
Homo sapiens
Sequence modifications
A, B, C, D, E, F, G, H, I, J: 1 - 37 (UniProt: P10997)
PDBExternal DatabaseDetails
Pro 25Ala 58engineered mutation
Nh2 38-amidation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains10
Total formula weight39333.5
All*Total formula weight39333.5
*Water molecules are not included.

247536

PDB entries from 2026-01-14

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