8R1P
Pim1 in complex with 6-bromobenzo[d]oxazol-2-amine and Pimtide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Serine/threonine-protein kinase pim-1 | polymer | 313 | 35670.5 | 1 | UniProt (P11309) Pfam (PF00069) | Homo sapiens (human) | |
| 2 | B (C) | Pimtide | polymer | 14 | 1592.8 | 1 | Homo sapiens | ||
| 3 | C (A) | 4-(4-aminostyryl)benzoic acid | non-polymer | 239.3 | 1 | Chemie (XIP) | |||
| 4 | D, E (A, C) | water | water | 18.0 | 61 | Chemie (HOH) |
Sequence modifications
A: 1 - 312 (UniProt: P11309)
| PDB | External Database | Details |
|---|---|---|
| Ser 0 | - | expression tag |
| Gly 250 | Arg 250 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 37263.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 239.3 | |
| All* | Total formula weight | 37502.6 |
