8R02
Crystal structure of the retromer complex VPS29/VPS35 with the ligand bis-1,3-phenyl guanylhydrazone, 2a
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Vacuolar protein sorting-associated protein 29 | polymer | 185 | 20930.2 | 2 | UniProt (Q9UBQ0) Pfam (PF12850) | Homo sapiens (human) | |
| 2 | C, D (C, D) | Vacuolar protein sorting-associated protein 35 | polymer | 306 | 35243.1 | 2 | UniProt (Q96QK1) Pfam (PF03635) | Homo sapiens (human) | |
| 3 | E (D) | Bis-1,3-phenyl guanylhydrazon | non-polymer | 246.3 | 1 | Chemie (XFZ) | |||
| 4 | F, G, H, I (A, B, C, D) | water | water | 18.0 | 64 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 182 (UniProt: Q9UBQ0)
C, D: 476 - 780 (UniProt: Q96QK1)
| PDB | External Database | Details |
|---|---|---|
| Met -2 | - | initiating methionine |
| Glu -1 | - | expression tag |
| His 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Met 475 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 112346.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 246.3 | |
| All* | Total formula weight | 112592.8 |
