8QYU
Beta-cardiac myosin S1 fragment in the pre-powerstroke state complexed to Omecamtiv mecarbil
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Myosin-7 | polymer | 810 | 92693.1 | 2 | UniProt (Q9BE39) Pfam (PF02736) Pfam (PF00063) | Bos taurus (cattle) | |
| 2 | C, D (G, H) | Myosin light chain 3 | polymer | 199 | 21968.0 | 2 | UniProt (P85100) | Bos taurus (cattle) | |
| 3 | E, M (A, B) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 2 | Chemie (ADP) | |||
| 4 | F, N (A, B) | VANADATE ION | non-polymer | 114.9 | 2 | Chemie (VO4) | |||
| 5 | G, O (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 6 | H, P, Q (A, B) | FORMIC ACID | non-polymer | 46.0 | 3 | Chemie (FMT) | |||
| 7 | I, J, K, R (A, B) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 4 | Chemie (DMS) | |||
| 8 | L, V (A, B) | methyl 4-(2-fluoro-3-{[(6-methylpyridin-3-yl)carbamoyl]amino}benzyl)piperazine-1-carboxylate | non-polymer | 401.4 | 2 | Chemie (2OW) | |||
| 9 | S, T (B) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 10 | U (B) | MALONIC ACID | non-polymer | 104.1 | 1 | Chemie (MLA) | |||
| 11 | W, X, Y, Z (A, B, G, H) | water | water | 18.0 | 769 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 229322.3 | |
| Non-Polymers* | Number of molecules | 18 |
| Total formula weight | 2674.6 | |
| All* | Total formula weight | 231997.0 |
