8QYR
Beta-cardiac myosin motor domain in the pre-powerstroke state complexed to Mavacamten
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (B) | Myosin-7 | polymer | 781 | 89196.0 | 1 | UniProt (Q9BE39) Pfam (PF02736) Pfam (PF00063) | Bos taurus (cattle) | |
| 2 | B (B) | Mavacamten | non-polymer | 273.3 | 1 | Chemie (XB2) | |||
| 3 | C, D, F (B) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 4 | E (B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 5 | G (B) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 6 | H (B) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (ADP) | |||
| 7 | I (B) | BERYLLIUM TRIFLUORIDE ION | non-polymer | 66.0 | 1 | Chemie (BEF) | |||
| 8 | J (B) | water | water | 18.0 | 424 | Chemie (HOH) |
Sequence modifications
B: 1 - 781 (UniProt: Q9BE39)
| PDB | External Database | Details |
|---|---|---|
| Asp 735 | Phe 735 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 89196.0 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1141.1 | |
| All* | Total formula weight | 90337.1 |
