8QYN
Human 20S proteasome assembly intermediate structure 5
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Proteasome subunit alpha type-2 | polymer | 234 | 25927.5 | 1 | UniProt (P25787) Pfam (PF10584) Pfam (PF00227) In PDB | Homo sapiens (human) | Macropain subunit C3,Multicatalytic endopeptidase complex subunit C3,Proteasome component C3 |
2 | B | Proteasome subunit alpha type-4 | polymer | 261 | 29525.8 | 1 | UniProt (P25789) Pfam (PF10584) Pfam (PF00227) In PDB | Homo sapiens (human) | Macropain subunit C9,Multicatalytic endopeptidase complex subunit C9,Proteasome component C9,Proteasome subunit L |
3 | C | Proteasome subunit alpha type-7 | polymer | 248 | 27929.9 | 1 | UniProt (O14818) Pfam (PF10584) Pfam (PF00227) In PDB | Homo sapiens (human) | Proteasome subunit RC6-1,Proteasome subunit XAPC7 |
4 | D | Proteasome subunit alpha type-5 | polymer | 242 | 26462.0 | 1 | UniProt (P28066) Pfam (PF10584) Pfam (PF00227) In PDB | Homo sapiens (human) | Macropain zeta chain,Multicatalytic endopeptidase complex zeta chain,Proteasome zeta chain |
5 | E | Proteasome subunit alpha type-1 | polymer | 264 | 29621.7 | 1 | UniProt (P25786) Pfam (PF00227) Pfam (PF10584) In PDB | Homo sapiens (human) | |
6 | F | Proteasome subunit alpha type-3 | polymer | 255 | 28469.3 | 1 | UniProt (P25788) Pfam (PF10584) Pfam (PF00227) In PDB | Homo sapiens (human) | Macropain subunit C8,Multicatalytic endopeptidase complex subunit C8,Proteasome component C8 |
7 | G | Proteasome subunit alpha type-6 | polymer | 246 | 27432.5 | 1 | UniProt (P60900) Pfam (PF10584) Pfam (PF00227) In PDB | Homo sapiens (human) | 27 kDa prosomal protein,p27K,Macropain iota chain,Multicatalytic endopeptidase complex iota chain,Proteasome iota chain |
8 | H | Proteasome maturation protein | polymer | 142 | 15831.0 | 1 | UniProt (Q9Y244) Pfam (PF05348) In PDB | Homo sapiens (human) | |
9 | I | Proteasome assembly chaperone 1 | polymer | 288 | 32891.9 | 1 | UniProt (O95456) Pfam (PF16094) In PDB | Homo sapiens (human) | PAC-1,Chromosome 21 leucine-rich protein,C21-LRP,Down syndrome critical region protein 2 |
10 | J | Proteasome assembly chaperone 2 | polymer | 265 | 29449.1 | 1 | UniProt (Q969U7) Pfam (PF09754) In PDB | Homo sapiens (human) | |
11 | K | Proteasome subunit beta type-7 | polymer | 332 | 35490.4 | 1 | UniProt (Q99436) Pfam (PF00227) Pfam (PF12465) In PDB | Homo sapiens (human) | |
12 | L | Proteasome subunit beta type-3 | polymer | 205 | 22972.9 | 1 | UniProt (P49720) Pfam (PF00227) In PDB | Homo sapiens (human) | Proteasome chain 13,Proteasome component C10-II,Proteasome theta chain |
13 | M | Proteasome subunit beta type-2 | polymer | 202 | 22890.3 | 1 | UniProt (P49721) Pfam (PF00227) In PDB | Homo sapiens (human) | |
14 | N | Proteasome subunit beta type-5 | polymer | 264 | 28536.3 | 1 | UniProt (P28074) Pfam (PF00227) In PDB | Homo sapiens (human) | |
15 | O | Proteasome subunit beta type-1 | polymer | 241 | 26522.4 | 1 | UniProt (P20618) Pfam (PF00227) In PDB | Homo sapiens (human) | Macropain subunit C5,Multicatalytic endopeptidase complex subunit C5,Proteasome component C5,Proteasome gamma chain |
16 | P | Proteasome subunit beta type-4 | polymer | 264 | 29219.1 | 1 | UniProt (P28070) Pfam (PF00227) In PDB | Homo sapiens (human) | 26 kDa prosomal protein,HsBPROS26,PROS-26,Macropain beta chain,Multicatalytic endopeptidase complex beta chain,Proteasome beta chain,Proteasome chain 3,HsN3 |
17 | Q | Proteasome subunit beta type-6 | polymer | 239 | 25335.6 | 1 | UniProt (P28072) Pfam (PF00227) In PDB | Homo sapiens (human) |
Sequence modifications
D: 1 - 241 (UniProt: P28066)
E: 1 - 263 (UniProt: P25786)
H: 1 - 141 (UniProt: Q9Y244)
J: 1 - 264 (UniProt: Q969U7)
K: 1 - 238 (UniProt: Q99436)
M: 1 - 201 (UniProt: P49721)
N: 1 - 263 (UniProt: P28074)
P: 1 - 264 (UniProt: P28070)
Q: 1 - 239 (UniProt: P28072)
PDB | External Database | Details |
---|---|---|
Ace 0 | - | acetylation |
PDB | External Database | Details |
---|---|---|
Ace 0 | - | acetylation |
PDB | External Database | Details |
---|---|---|
Ace 0 | - | acetylation |
PDB | External Database | Details |
---|---|---|
Ace 0 | - | acetylation |
PDB | External Database | Details |
---|---|---|
Glu 238 | - | expression tag |
Asp 238 | - | expression tag |
Leu 238 | - | expression tag |
Tyr 238 | - | expression tag |
Phe 238 | - | expression tag |
Gln 238 | - | expression tag |
Ser 238 | - | expression tag |
Val 238 | - | expression tag |
Asp 238 | - | expression tag |
Ser 238 | - | expression tag |
Ala 238 | - | expression tag |
Trp 238 | - | expression tag |
Ser 239 | - | expression tag |
His 239 | - | expression tag |
Pro 239 | - | expression tag |
Gln 239 | - | expression tag |
Phe 239 | - | expression tag |
Glu 239 | - | expression tag |
Lys 239 | - | expression tag |
Gly 239 | - | expression tag |
Gly 239 | - | expression tag |
Gly 239 | - | expression tag |
Ser 239 | - | expression tag |
Gly 239 | - | expression tag |
Gly 239 | - | expression tag |
Gly 239 | - | expression tag |
Ser 239 | - | expression tag |
Gly 239 | - | expression tag |
Gly 239 | - | expression tag |
Ser 239 | - | expression tag |
Ala 239 | - | expression tag |
Trp 239 | - | expression tag |
Ser 239 | - | expression tag |
His 239 | - | expression tag |
Pro 239 | - | expression tag |
Gln 239 | - | expression tag |
Phe 239 | - | expression tag |
Glu 239 | - | expression tag |
Lys 240 | - | expression tag |
Unk 247 | - | expression tag |
Unk 248 | - | expression tag |
Unk 249 | - | expression tag |
Unk 250 | - | expression tag |
Unk 251 | - | expression tag |
Unk 252 | - | expression tag |
Unk 253 | - | expression tag |
Unk 254 | - | expression tag |
Unk 255 | - | expression tag |
Unk 256 | - | expression tag |
Unk 257 | - | expression tag |
Unk 258 | - | expression tag |
Unk 259 | - | expression tag |
Unk 260 | - | expression tag |
Unk 261 | - | expression tag |
Unk 262 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Ace 0 | - | acetylation |
PDB | External Database | Details |
---|---|---|
Ace 0 | - | acetylation |
PDB | External Database | Details |
---|---|---|
Thr 234 | Ile 234 | variant |
PDB | External Database | Details |
---|---|---|
Gly 145 | Val 145 | variant |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 17 |
Total formula weight | 464507.6 | |
All* | Total formula weight | 464507.6 |