8QYJ
Human 20S proteasome assembly structure 1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Proteasome subunit alpha type-2 | polymer | 234 | 25927.5 | 1 | UniProt (P25787) Pfam (PF10584) Pfam (PF00227) | Homo sapiens (human) | Macropain subunit C3,Multicatalytic endopeptidase complex subunit C3,Proteasome component C3 |
| 2 | B (B) | Proteasome subunit alpha type-4 | polymer | 261 | 29525.8 | 1 | UniProt (P25789) Pfam (PF10584) Pfam (PF00227) | Homo sapiens (human) | Macropain subunit C9,Multicatalytic endopeptidase complex subunit C9,Proteasome component C9,Proteasome subunit L |
| 3 | C (C) | Proteasome subunit alpha type-7 | polymer | 248 | 27929.9 | 1 | UniProt (O14818) Pfam (PF10584) Pfam (PF00227) | Homo sapiens (human) | Proteasome subunit RC6-1,Proteasome subunit XAPC7 |
| 4 | D (D) | Proteasome subunit alpha type-5 | polymer | 242 | 26462.0 | 1 | UniProt (P28066) Pfam (PF10584) Pfam (PF00227) | Homo sapiens (human) | Macropain zeta chain,Multicatalytic endopeptidase complex zeta chain,Proteasome zeta chain |
| 5 | E (E) | Proteasome subunit alpha type-1 | polymer | 264 | 29621.7 | 1 | UniProt (P25786) Pfam (PF00227) Pfam (PF10584) | Homo sapiens (human) | |
| 6 | F (F) | Proteasome subunit alpha type-3 | polymer | 255 | 28469.3 | 1 | UniProt (P25788) Pfam (PF10584) Pfam (PF00227) | Homo sapiens (human) | Macropain subunit C8,Multicatalytic endopeptidase complex subunit C8,Proteasome component C8 |
| 7 | G (G) | Proteasome subunit alpha type-6 | polymer | 246 | 27432.5 | 1 | UniProt (P60900) Pfam (PF10584) Pfam (PF00227) | Homo sapiens (human) | 27 kDa prosomal protein,p27K,Macropain iota chain,Multicatalytic endopeptidase complex iota chain,Proteasome iota chain |
| 8 | H (H) | Proteasome maturation protein | polymer | 141 | 15805.0 | 1 | UniProt (Q9Y244) Pfam (PF05348) | Homo sapiens (human) | Proteassemblin,Protein UMP1 homolog,hUMP1,Voltage-gated K channel beta subunit 4.1 |
| 9 | I (I) | Proteasome assembly chaperone 1 | polymer | 288 | 32891.9 | 1 | UniProt (O95456) Pfam (PF16094) | Homo sapiens (human) | PAC-1,Chromosome 21 leucine-rich protein,C21-LRP,Down syndrome critical region protein 2 |
| 10 | J (J) | Proteasome assembly chaperone 2 | polymer | 265 | 29449.1 | 1 | UniProt (Q969U7) Pfam (PF09754) | Homo sapiens (human) | |
| 11 | K (K) | Proteasome subunit beta type-7 | polymer | 316 | 34128.7 | 1 | UniProt (Q99436) Pfam (PF00227) Pfam (PF12465) | Homo sapiens (human) | |
| 12 | L (L) | Proteasome assembly chaperone 3 | polymer | 122 | 13118.4 | 1 | UniProt (Q9BT73) Pfam (PF10178) | Homo sapiens (human) | PAC-3,hPAC3 |
| 13 | M (M) | Proteasome assembly chaperone 4 | polymer | 123 | 13789.6 | 1 | UniProt (Q5JS54) Pfam (PF16093) | Homo sapiens (human) | PAC-4,hPAC4 |
Sequence modifications
D: 1 - 241 (UniProt: P28066)
E: 1 - 263 (UniProt: P25786)
J: 1 - 264 (UniProt: Q969U7)
K: 1 - 277 (UniProt: Q99436)
| PDB | External Database | Details |
|---|---|---|
| Ace 0 | - | acetylation |
| PDB | External Database | Details |
|---|---|---|
| Ace 0 | - | acetylation |
| PDB | External Database | Details |
|---|---|---|
| Ace 0 | - | acetylation |
| PDB | External Database | Details |
|---|---|---|
| Glu 278 | - | expression tag |
| Asp 279 | - | expression tag |
| Leu 280 | - | expression tag |
| Tyr 281 | - | expression tag |
| Phe 282 | - | expression tag |
| Gln 283 | - | expression tag |
| Ser 284 | - | expression tag |
| Val 285 | - | expression tag |
| Asp 286 | - | expression tag |
| Ser 287 | - | expression tag |
| Ala 288 | - | expression tag |
| Trp 289 | - | expression tag |
| Ser 290 | - | expression tag |
| His 291 | - | expression tag |
| Pro 292 | - | expression tag |
| Gln 293 | - | expression tag |
| Phe 294 | - | expression tag |
| Glu 295 | - | expression tag |
| Lys 296 | - | expression tag |
| Gly 297 | - | expression tag |
| Gly 298 | - | expression tag |
| Gly 299 | - | expression tag |
| Ser 300 | - | expression tag |
| Gly 301 | - | expression tag |
| Gly 302 | - | expression tag |
| Gly 303 | - | expression tag |
| Ser 304 | - | expression tag |
| Gly 305 | - | expression tag |
| Gly 306 | - | expression tag |
| Ser 307 | - | expression tag |
| Ala 308 | - | expression tag |
| Trp 309 | - | expression tag |
| Ser 310 | - | expression tag |
| His 311 | - | expression tag |
| Pro 312 | - | expression tag |
| Gln 313 | - | expression tag |
| Phe 314 | - | expression tag |
| Glu 315 | - | expression tag |
| Lys 316 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 13 |
| Total formula weight | 334551.4 | |
| All* | Total formula weight | 334551.4 |
