8QXM

Cryo-EM structure of tetrameric human SAMHD1 State III - Relaxed

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Deoxynucleoside triphosphate triphosphohydrolase SAMHD1	polymer	626	72305.4	4	UniProt (Q9Y3Z3) Pfam (PF07647) Pfam (PF01966)	Homo sapiens (human)
2	E, K, S, Y (A, B, C, D)	FE (III) ION	non-polymer		55.8	4	Chemie (FE)
3	AA, F, G, L, M... (D, A, B, C)	MAGNESIUM ION	non-polymer		24.3	10	Chemie (MG)
4	H, P, Q, W (A, B, C, D)	2'-DEOXYADENOSINE 5'-TRIPHOSPHATE	non-polymer		491.2	4	Chemie (DTP)
5	I, J, R, X (B, C, D)	GUANOSINE-5'-TRIPHOSPHATE	non-polymer		523.2	4	Chemie (GTP)
6	BA, O (D, B)	2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE	non-polymer		467.2	2	Chemie (DCP)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	289221.7
Non-Polymers*	Number of molecules	24
	Total formula weight	5458.2
All*	Total formula weight	294679.8

*Water molecules are not included.