8QXL
Cryo-EM structure of tetrameric human SAMHD1 State II - Hemi-relaxed
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | polymer | 626 | 72305.4 | 4 | UniProt (Q9Y3Z3) Pfam (PF07647) Pfam (PF01966) | Homo sapiens (human) | |
| 2 | AA, E, K, T (D, A, C) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 4 | Chemie (GTP) PubChem (177679032) PubChem (135400627) PubChem (135487750) PubChem (136088935) PubChem (136803486) PubChem (135398633) PubChem (135544356) PubChem (135547949) PubChem (135600366) PubChem (135749822) PubChem (136005188) PubChem (136073923) PubChem (136240914) PubChem (136664747) PubChem (136772743) PubChem (136772744) PubChem (136803487) PubChem (137286749) PubChem (164715984) PubChem (171699466) | |||
| 3 | BA, F, N, U (D, A, B, C) | FE (III) ION | non-polymer | 55.8 | 4 | Chemie (FE) PubChem (29936) | |||
| 4 | CA, DA, EA, G, H... (D, A, B, C) | MAGNESIUM ION | non-polymer | 24.3 | 10 | Chemie (MG) PubChem (888) | |||
| 5 | I, X (A, C) | 2'-DEOXYCYTIDINE | non-polymer | 227.2 | 2 | Chemie (DCZ) | |||
| 6 | J, Y (A, C) | TRIPHOSPHATE | non-polymer | 258.0 | 2 | Chemie (3PO) PubChem (983) | |||
| 7 | L, M, S, Z (A, B, D) | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE | non-polymer | 491.2 | 4 | Chemie (DTP) PubChem (622) PubChem (15993) PubChem (44119995) PubChem (448808) PubChem (46936612) PubChem (57233913) PubChem (91632917) PubChem (92341128) PubChem (92449119) PubChem (92449120) PubChem (89346292) PubChem (129069956) PubChem (171699368) | |||
| 8 | FA, R (D, B) | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE | non-polymer | 467.2 | 2 | Chemie (DCP) PubChem (65091) PubChem (44119993) PubChem (472334) PubChem (46936621) PubChem (53393445) PubChem (57187895) PubChem (625) PubChem (92436637) PubChem (92449132) PubChem (92449133) PubChem (121522025) PubChem (129069886) PubChem (171699322) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 289221.7 | |
| Non-Polymers* | Number of molecules | 28 |
| Total formula weight | 6428.5 | |
| All* | Total formula weight | 295650.2 |
