8QWY
Crystal structure of human Casein Kinase II subunit alpha (CK2a1) in complex with 4-(6-((5-isopropoxy-2-methoxyphenyl)amino)pyrazin-2-yl)benzoic acid
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Casein kinase II subunit alpha | polymer | 338 | 40328.0 | 2 | UniProt (P68400) Pfam (PF00069) | Homo sapiens (human) | CK II alpha |
| 2 | C, D, E, F, G... (A, B) | SULFATE ION | non-polymer | 96.1 | 12 | Chemie (SO4) | |||
| 3 | I, P (A, B) | 4-[6-[(2-methoxy-5-propan-2-yloxy-phenyl)amino]pyrazin-2-yl]benzoic acid | non-polymer | 379.4 | 2 | Chemie (X59) PubChem (169503067) | |||
| 4 | Q, R (A, B) | water | water | 18.0 | 16 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 337 (UniProt: P68400)
| PDB | External Database | Details |
|---|---|---|
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 80656.0 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 1911.6 | |
| All* | Total formula weight | 82567.5 |
