8QU7
Crystal structure of the Plasmodium falciparum Apical membrane antigen (AMA1) in complex with single domain i-body WD34
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (E) | Apical membrane antigen 1 | polymer | 362 | 41462.4 | 1 | UniProt (P22621) Pfam (PF02430) UniProt (by SIFTS) (Q7KQK5) | Plasmodium falciparum 3D7 | Merozoite surface antigen |
| 2 | B (A) | single domain i-body WD34 | polymer | 126 | 13803.4 | 1 | Homo sapiens | ||
| 3 | C (E) | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 1 | Chemie (MPD) | |||
| 4 | D (E) | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | non-polymer | 238.3 | 1 | Chemie (EPE) | |||
| 5 | E (E) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 6 | F (E) | water | water | 18.0 | 65 | Chemie (HOH) |
Sequence modifications
E: 97 - 438 (UniProt: P22621)
| PDB | External Database | Details |
|---|---|---|
| Met 77 | - | initiating methionine |
| Gly 78 | - | expression tag |
| Ser 79 | - | expression tag |
| Ser 80 | - | expression tag |
| His 81 | - | expression tag |
| His 82 | - | expression tag |
| His 83 | - | expression tag |
| His 84 | - | expression tag |
| His 85 | - | expression tag |
| His 86 | - | expression tag |
| Ser 87 | - | expression tag |
| Ser 88 | - | expression tag |
| Gly 89 | - | expression tag |
| Glu 90 | - | expression tag |
| Asn 91 | - | expression tag |
| Leu 92 | - | expression tag |
| Tyr 93 | - | expression tag |
| Phe 94 | - | expression tag |
| Gln 95 | - | expression tag |
| Gly 96 | - | expression tag |
| Pro 330 | Ser 330 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 55265.8 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 379.5 | |
| All* | Total formula weight | 55645.3 |
