8QSC
Ternary structure of 14-3-3s, ARAF phosphopeptide (pS214) and compound 22 (1083853).
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, J) | 14-3-3 protein sigma | polymer | 236 | 26542.9 | 2 | UniProt (P31947) Pfam (PF00244) | Homo sapiens (human) | Epithelial cell marker protein 1,Stratifin |
| 2 | B, D (H, S) | ARAF peptide pS214 | polymer | 11 | 1324.4 | 2 | Homo sapiens | ||
| 3 | E, J (A, J) | ~{N}-[[1-(4-bromophenyl)sulfonylpiperidin-4-yl]methyl]-2-chloranyl-ethanamide | non-polymer | 409.7 | 2 | Chemie (WPN) | |||
| 4 | F, G, H, L, M (A, J) | MAGNESIUM ION | non-polymer | 24.3 | 5 | Chemie (MG) | |||
| 5 | I, K (A, J) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 6 | N, O, P, Q (A, H, J, S) | water | water | 18.0 | 425 | Chemie (HOH) |
Sequence modifications
A, J: 1 - 231 (UniProt: P31947)
| PDB | External Database | Details |
|---|---|---|
| Gly -4 | - | expression tag |
| Ala -3 | - | expression tag |
| Met -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 55734.6 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1011.9 | |
| All* | Total formula weight | 56746.5 |
