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8QRO

ASCT2 trimer in lipid nanodiscs with bound glutamine and Na+ ions in the outward-facing state (OFS)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C
(A, B, C)
Neutral amino acid transporter B(0)polymer54757467.83UniProt (Q15758)
Pfam (PF00375)
Homo sapiens (human)ATB(0),Baboon M7 virus receptor,RD114/simian type D retrovirus receptor,Sodium-dependent neutral amino acid transporter type 2,Solute carrier family 1 member 5
2D, E, F, H, I...
(A, B, C)
SODIUM IONnon-polymer23.09Chemie (NA)
3G, K, O
(A, B, C)
GLUTAMINEnon-polymer146.13Chemie (GLN)
Sequence modifications
A, B, C: 1 - 541 (UniProt: Q15758)
PDBExternal DatabaseDetails
His 542-expression tag
His 543-expression tag
His 544-expression tag
His 545-expression tag
His 546-expression tag
His 547-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight172403.4
Non-Polymers*Number of molecules12
Total formula weight645.3
All*Total formula weight173048.7
*Water molecules are not included.

246905

PDB entries from 2025-12-31

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