8QRN
mt-SSU in GTPBP8 knock-out cells, state 4
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | 12S mitochondrial rRNA | polymer | 955 | 306547.5 | 1 | GenBank (OM714795.1) | Homo sapiens (human) | |
| 2 | B | 28S ribosomal protein S2, mitochondrial | polymer | 296 | 33298.2 | 1 | UniProt (Q9Y399) Pfam (PF00318) In PDB | Homo sapiens (human) | MRP-S2,S2mt,Mitochondrial small ribosomal subunit protein uS2m |
| 3 | C | 28S ribosomal protein S24, mitochondrial | polymer | 167 | 19046.2 | 1 | UniProt (Q96EL2) Pfam (PF14955) In PDB | Homo sapiens (human) | MRP-S24,S24mt,Mitochondrial small ribosomal subunit protein uS3m,bMRP-47,bMRP47 |
| 4 | D | 28S ribosomal protein S5, mitochondrial | polymer | 430 | 48094.6 | 1 | UniProt (P82675) Pfam (PF21251) Pfam (PF00333) Pfam (PF03719) In PDB | Homo sapiens (human) | MRP-S5,S5mt,Mitochondrial small ribosomal subunit protein uS5m |
| 5 | E | 28S ribosomal protein S6, mitochondrial | polymer | 125 | 14250.6 | 1 | UniProt (P82932) Pfam (PF01250) In PDB | Homo sapiens (human) | MRP-S6,S6mt,Mitochondrial small ribosomal subunit protein bS6m |
| 6 | F | 28S ribosomal protein S7, mitochondrial | polymer | 242 | 28186.2 | 1 | UniProt (Q9Y2R9) Pfam (PF00177) In PDB | Homo sapiens (human) | MRP-S7,S7mt,Mitochondrial small ribosomal subunit protein uS7m,bMRP-27a,bMRP27a |
| 7 | G | 28S ribosomal protein S9, mitochondrial | polymer | 396 | 45909.9 | 1 | UniProt (P82933) Pfam (PF00380) In PDB | Homo sapiens (human) | MRP-S9,S9mt,Mitochondrial small ribosomal subunit protein uS9m |
| 8 | H | 28S ribosomal protein S10, mitochondrial | polymer | 201 | 23033.5 | 1 | UniProt (P82664) Pfam (PF00338) In PDB | Homo sapiens (human) | MRP-S10,S10mt,Mitochondrial small ribosomal subunit protein uS10m |
| 9 | I | 28S ribosomal protein S11, mitochondrial | polymer | 194 | 20648.8 | 1 | UniProt (P82912) Pfam (PF00411) In PDB | Homo sapiens (human) | S11mt,Cervical cancer proto-oncogene 2 protein,HCC-2,Mitochondrial small ribosomal subunit protein uS11m |
| 10 | J | 28S ribosomal protein S12, mitochondrial | polymer | 138 | 15200.9 | 1 | UniProt (O15235) Pfam (PF00164) In PDB | Homo sapiens (human) | MRP-S12,S12mt,MT-RPS12,Mitochondrial small ribosomal subunit protein uS12m |
| 11 | K | 28S ribosomal protein S14, mitochondrial | polymer | 128 | 15168.8 | 1 | UniProt (O60783) Pfam (PF00253) In PDB | Homo sapiens (human) | MRP-S14,S14mt,Mitochondrial small ribosomal subunit protein uS14m |
| 12 | L | 28S ribosomal protein S15, mitochondrial | polymer | 257 | 29903.3 | 1 | UniProt (P82914) Pfam (PF00312) In PDB | Homo sapiens (human) | MRP-S15,S15mt,Mitochondrial small ribosomal subunit protein uS15m |
| 13 | M | 28S ribosomal protein S16, mitochondrial | polymer | 137 | 15371.9 | 1 | UniProt (Q9Y3D3) Pfam (PF00886) In PDB | Homo sapiens (human) | MRP-S16,S16mt,Mitochondrial small ribosomal subunit protein bS16m |
| 14 | N | 28S ribosomal protein S17, mitochondrial | polymer | 130 | 14526.1 | 1 | UniProt (Q9Y2R5) Pfam (PF00366) In PDB | Homo sapiens (human) | MRP-S17,S17mt,Mitochondrial small ribosomal subunit protein uS17m |
| 15 | O | 28S ribosomal protein S18b, mitochondrial | polymer | 258 | 29440.6 | 1 | UniProt (Q9Y676) Pfam (PF01084) In PDB | Homo sapiens (human) | MRP-S18-b,Mrps18-b,S18mt-b,28S ribosomal protein S18-2,mitochondrial,MRP-S18-2,Mitochondrial small ribosomal subunit protein bS18b,Mitochondrial small ribosomal subunit protein mS40 |
| 16 | P | 28S ribosomal protein S18c, mitochondrial | polymer | 142 | 15876.8 | 1 | UniProt (Q9Y3D5) Pfam (PF01084) In PDB | Homo sapiens (human) | MRP-S18-c,Mrps18-c,S18mt-c,28S ribosomal protein S18-1,mitochondrial,MRP-S18-1,Mitochondrial small ribosomal subunit protein bS18c,Mitochondrial small ribosomal subunit protein bS18m |
| 17 | Q | 28S ribosomal protein S21, mitochondrial | polymer | 86 | 10675.5 | 1 | UniProt (P82921) Pfam (PF01165) In PDB | Homo sapiens (human) | S21mt,Mitochondrial small ribosomal subunit protein bS21m |
| 18 | R | 28S ribosomal protein S22, mitochondrial | polymer | 360 | 41337.3 | 1 | UniProt (P82650) Pfam (PF10245) In PDB | Homo sapiens (human) | MRP-S22,S22mt,Mitochondrial small ribosomal subunit protein mS22 |
| 19 | S | 28S ribosomal protein S23, mitochondrial | polymer | 190 | 21805.7 | 1 | UniProt (Q9Y3D9) Pfam (PF10484) In PDB | Homo sapiens (human) | MRP-S23,S23mt,Mitochondrial small ribosomal subunit protein mS23 |
| 20 | T | 28S ribosomal protein S25, mitochondrial | polymer | 173 | 20146.4 | 1 | UniProt (P82663) Pfam (PF05047) In PDB | Homo sapiens (human) | MRP-S25,S25mt,Mitochondrial small ribosomal subunit protein mS25 |
| 21 | U | 28S ribosomal protein S26, mitochondrial | polymer | 205 | 24259.8 | 1 | UniProt (Q9BYN8) Pfam (PF14943) In PDB | Homo sapiens (human) | MRP-S26,S26mt,28S ribosomal protein S13,mitochondrial,MRP-S13,S13mt,Mitochondrial small ribosomal subunit protein mS26 |
| 22 | V | 28S ribosomal protein S27, mitochondrial | polymer | 414 | 47669.3 | 1 | UniProt (Q92552) Pfam (PF10037) In PDB | Homo sapiens (human) | MRP-S27,S27mt,Mitochondrial ribosomal protein S27,Mitochondrial small ribosomal subunit protein mS27 |
| 23 | W | 28S ribosomal protein S28, mitochondrial | polymer | 187 | 20878.8 | 1 | UniProt (Q9Y2Q9) Pfam (PF10246) In PDB | Homo sapiens (human) | MRP-S28,S28mt,28S ribosomal protein S35,mitochondrial,MRP-S35,S35mt,Mitochondrial small ribosomal subunit protein bS1m |
| 24 | X | 28S ribosomal protein S29, mitochondrial | polymer | 398 | 45634.4 | 1 | UniProt (P51398) Pfam (PF10236) In PDB | Homo sapiens (human) | MRP-S29,S29mt,Death-associated protein 3,DAP-3,Ionizing radiation resistance conferring protein,Mitochondrial small ribosomal subunit protein mS29 |
| 25 | Y | 28S ribosomal protein S31, mitochondrial | polymer | 395 | 45391.5 | 1 | UniProt (Q92665) Pfam (PF15433) In PDB | Homo sapiens (human) | MRP-S31,S31mt,Imogen 38,Mitochondrial small ribosomal subunit protein mS31 |
| 26 | Z | 28S ribosomal protein S33, mitochondrial | polymer | 106 | 12657.8 | 1 | UniProt (Q9Y291) Pfam (PF08293) In PDB | Homo sapiens (human) | MRP-S33,S33mt,Mitochondrial small ribosomal subunit protein mS33 |
| 27 | 0 | 28S ribosomal protein S34, mitochondrial | polymer | 218 | 25695.5 | 1 | UniProt (P82930) Pfam (PF16053) In PDB | Homo sapiens (human) | S34mt,Mitochondrial small ribosomal subunit protein mS34 |
| 28 | 1 | 28S ribosomal protein S35, mitochondrial | polymer | 323 | 36898.3 | 1 | UniProt (P82673) Pfam (PF10213) In PDB | Homo sapiens (human) | MRP-S35,S35mt,28S ribosomal protein S28,mitochondrial,MRP-S28,S28mt,Mitochondrial small ribosomal subunit protein mS35 |
| 29 | 2 | Coiled-coil-helix-coiled-coil-helix domain-containing protein 1 | polymer | 117 | 13409.7 | 1 | UniProt (Q96BP2) Pfam (PF06747) In PDB | Homo sapiens (human) | 28S ribosomal protein S37,mitochondrial,MRP-S37,Mitochondrial small ribosomal subunit protein mS37,Nuclear protein C2360 |
| 30 | 3 | Aurora kinase A-interacting protein | polymer | 199 | 22395.3 | 1 | UniProt (Q9NWT8) Pfam (PF08213) In PDB | Homo sapiens (human) | AURKA-interacting protein,28S ribosomal protein S38,mitochondrial,MRP-S38,Mitochondrial small ribosomal subunit protein mS38 |
| 31 | 4 | Pentatricopeptide repeat domain-containing protein 3, mitochondrial | polymer | 689 | 78648.5 | 1 | UniProt (Q96EY7) Pfam (PF22330) Pfam (PF13812) In PDB | Homo sapiens (human) | 28S ribosomal protein S39,mitochondrial,MRP-S39,Mitochondrial small ribosomal subunit protein mS39,Transformation-related gene 15 protein,TRG-15 |
| 32 | 5 | fMet-tRNAMet | polymer | 71 | 22692.5 | 1 | Homo sapiens (human) | ||
| 33 | 7 | Translation initiation factor IF-2, mitochondrial | polymer | 691 | 76873.0 | 1 | UniProt (P46199) Pfam (PF11987) Pfam (PF00009) Pfam (PF22042) In PDB | Homo sapiens (human) | IF-2(Mt),IF-2Mt,IF2(mt) |
| 34 | 6 | mRNA | polymer | 3 | 919.6 | 1 | Homo sapiens (human) | ||
| 35 | A | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 1 | Chemie (NAD) | |||
| 36 | A | SPERMINE | non-polymer | 202.3 | 1 | Chemie (SPM) | |||
| 37 | A | STREPTOMYCIN | non-polymer | 581.6 | 1 | Chemie (SRY) | |||
| 38 | A, B, X, 3, 7 | MAGNESIUM ION | non-polymer | 24.3 | 58 | Chemie (MG) | |||
| 39 | A, 7 | POTASSIUM ION | non-polymer | 39.1 | 18 | Chemie (K) | |||
| 40 | O | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 41 | P, T | FE2/S2 (INORGANIC) CLUSTER | non-polymer | 175.8 | 2 | Chemie (FES) | |||
| 42 | X | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 1 | Chemie (ATP) | |||
| 43 | X | PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | non-polymer | 522.2 | 1 | Chemie (GNP) | |||
| 44 | 5 | N-FORMYLMETHIONINE | non-polymer | 177.2 | 1 | Chemie (FME) | |||
| 45 | 7 | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 1 | Chemie (GTP) | |||
| 46 | water | water | 18.0 | 7 | Chemie (HOH) |
Sequence modifications
A: 648 - 1602 (GenBank: OM714795.1)
Q: 2 - 87 (UniProt: P82921)
7: 38 - 727 (UniProt: P46199)
| PDB | External Database | Details |
|---|---|---|
| G 709 | A 710 | variant |
| PDB | External Database | Details |
|---|---|---|
| Arg 50 | Cys 50 | variant |
| PDB | External Database | Details |
|---|---|---|
| Met 37 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 34 |
| Total formula weight | 1242492.9 | |
| Non-Polymers* | Number of molecules | 86 |
| Total formula weight | 5707.6 | |
| All* | Total formula weight | 1248200.5 |
