8QNM

OPR3 with redesigned Loop 6 (9aa) in complex with NADPH4

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	12-oxophytodienoate reductase 3	polymer	397	43768.5	2	UniProt (Q9FEW9) Pfam (PF00724)	Solanum lycopersicum (tomato)
2	C, E (A, B)	FLAVIN MONONUCLEOTIDE	non-polymer		456.3	2	Chemie (FMN)
3	D, F (A, B)	[[(2R,3S,4R,5R)-5-(5-aminocarbonyl-3,4-dihydro-2H-pyridin-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-3-oxidanyl-4-phosphonooxy-oxolan-2-yl]methyl hydrogen phosphate	non-polymer		747.4	2	Chemie (5J8)
4	G, H (A, B)	water	water		18.0	331	Chemie (HOH)

Sequence modifications

A, B: 1 - 388 (UniProt: Q9FEW9)

PDB	External Database	Details
Met -8	-	initiating methionine
Ala -7	-	expression tag
Ser -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag
Ser 284	Tyr 284	engineered mutation
Asp 285	Val 285	engineered mutation
Lys 286	Ala 286	engineered mutation
Gly 287	Tyr 287	engineered mutation
-	Gly 288	deletion
-	Gln 289	deletion
-	Thr 290	deletion
-	Glu 291	deletion
-	Ala 292	deletion
-	Gly 293	deletion
-	Arg 294	deletion
-	Leu 295	deletion

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	87537.0
Non-Polymers*	Number of molecules	4
	Total formula weight	2407.6
All*	Total formula weight	89944.6

*Water molecules are not included.