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8QL0

Structure of human PAD6 Phosphomimic mutant V10E/S446E, apo

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Protein-arginine deiminase type-6polymer69377759.01UniProt (Q6TGC4)
Pfam (PF08526)
Pfam (PF08527)
Pfam (PF03068)
Homo sapiens (human)Peptidyl arginine deiminase-like protein,Peptidylarginine deiminase VI,hPADVI,Protein-arginine deiminase type VI
2B, C, E, F
(A)
DI(HYDROXYETHYL)ETHERnon-polymer106.14Chemie (PEG)
3D
(A)
GLYCEROLnon-polymer92.11Chemie (GOL)
4G
(A)
PENTAETHYLENE GLYCOLnon-polymer238.31Chemie (1PE)
5H
(A)
CHLORIDE IONnon-polymer35.51Chemie (CL)
6I
(A)
waterwater18.0304Chemie (HOH)
Sequence modifications
A: 2 - 694 (UniProt: Q6TGC4)
PDBExternal DatabaseDetails
Glu 10Ser 10engineered mutation
Glu 446Ser 446engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight77759.0
Non-Polymers*Number of molecules7
Total formula weight790.3
All*Total formula weight78549.3
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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