8QIC
Structure-based identification of salicylic acid derivatives as malarial threonyl tRNA-synthetase inhibitors
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, D) | Threonine--tRNA ligase | polymer | 400 | 46568.0 | 2 | UniProt (B7M1C7) Pfam (PF00587) Pfam (PF03129) UniProt (by SIFTS) (P0A8M3) | Escherichia coli O8 | |
| 2 | C, F (A, D) | 2-oxidanyl-5-[[4-(phenylmethyl)phenyl]sulfamoyl]benzoic acid | non-polymer | 383.4 | 2 | Chemie (VL0) | |||
| 3 | D, G, H, I (A, D) | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
| 4 | E, J (A, D) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 5 | K, L (A, D) | water | water | 18.0 | 47 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 93136.0 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1266.0 | |
| All* | Total formula weight | 94402.0 |
