8QH0
Crystal structure of the SARS-CoV-2 RBD with the antibody Cv2.3194
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Spike protein S1 | polymer | 206 | 23068.7 | 1 | UniProt (P0DTC2) Pfam (PF09408) In PDB | Severe acute respiratory syndrome coronavirus 2 | |
2 | H | Cv2.3194 Heavy chain | polymer | 229 | 24379.3 | 1 | Homo sapiens | ||
3 | L | IGK@ protein | polymer | 211 | 22821.3 | 1 | UniProt (Q6PJF2) Pfam (PF07686) Pfam (PF07654) In PDB | Homo sapiens (human) | |
4 | B | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
5 | A | PROLINE | non-polymer | 115.1 | 1 | Chemie (PRO) | |||
6 | A, H | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
7 | water | water | 18.0 | 384 | Chemie (HOH) |
Sequence modifications
A: 331 - 528 (UniProt: P0DTC2)
L: 1 - 214 (UniProt: Q6PJF2)
PDB | External Database | Details |
---|---|---|
Phe 367 | Val 367 | variant |
Gly 529 | - | expression tag |
Ser 530 | - | expression tag |
Gly 531 | - | expression tag |
Asp 532 | - | expression tag |
Asp 533 | - | expression tag |
Asp 534 | - | expression tag |
Asp 535 | - | expression tag |
Lys 536 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Gly 9 | Ala 29 | conflict |
Ser 28 | Ile 48 | conflict |
Ser 32 | Ala 52 | conflict |
Ile 49 | Met 69 | conflict |
Tyr 50 | Phe 70 | conflict |
Ala 52 | Ser 72 | conflict |
Gly 61 | Asp 81 | conflict |
Ile 86 | Val 106 | conflict |
- | Tyr 112 | deletion |
- | Gly 113 | deletion |
- | Ser 114 | deletion |
- | Ser 115 | deletion |
Gly 92 | Gln 116 | conflict |
Val 93 | Gly 117 | conflict |
Gly 97 | Pro 121 | conflict |
Glu 102 | Asp 126 | conflict |
Asn 215 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 70269.3 | |
Branched | Number of molecules | 1 |
Total formula weight | 424.4 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 299.3 | |
All* | Total formula weight | 70993.0 |