8QF1

STRUCTURE OF THE CATALYTIC SUBUNIT OF PROTEIN KINASE CK2 (CK2ALPHA') IN COMPLEX WITH THE NON-HYDROLYZABLE GTP ANALOGUE GMPPNP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Casein kinase II subunit alpha'	polymer	364	42879.9	2	UniProt (P19784) Pfam (PF00069)	Homo sapiens (human)	CK II alpha'
2	C (A)	PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER	non-polymer		522.2	1	Chemie (GNP)
3	D, E, F (A, B)	MAGNESIUM ION	non-polymer		24.3	3	Chemie (MG)
4	G, H (A, B)	water	water		18.0	607	Chemie (HOH)

Sequence modifications

A, B: 1 - 350 (UniProt: P19784)

PDB	External Database	Details
Met -13	-	initiating methionine
Gly -12	-	expression tag
Ser -11	-	expression tag
Ser -10	-	expression tag
His -9	-	expression tag
His -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
Ser -3	-	expression tag
Gln -2	-	expression tag
Asp -1	-	expression tag
Pro 0	-	expression tag
Ser 336	Cys 336	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	85759.7
Non-Polymers*	Number of molecules	4
	Total formula weight	595.1
All*	Total formula weight	86354.8

*Water molecules are not included.