8QE3
Crystal structure of human MAT2a bound to S-Adenosylmethionine and Compound 31
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | S-adenosylmethionine synthase isoform type-2 | polymer | 397 | 43935.8 | 1 | UniProt (P31153) Pfam (PF00438) Pfam (PF02772) Pfam (PF02773) In PDB | Homo sapiens (human) | AdoMet synthase 2,Methionine adenosyltransferase 2,MAT 2,Methionine adenosyltransferase II,MAT-II |
2 | A | 3-cyclopropyl-6-(2-methylindazol-5-yl)-4-(6-methylpyridin-3-yl)-2~{H}-pyrazolo[4,3-b]pyridin-5-one | non-polymer | 396.4 | 1 | Chemie (U96) | |||
3 | A | S-ADENOSYLMETHIONINE | non-polymer | 398.4 | 1 | Chemie (SAM) | |||
4 | water | water | 18.0 | 361 | Chemie (HOH) |
Sequence modifications
A: 1 - 395 (UniProt: P31153)
PDB | External Database | Details |
---|---|---|
Gln -1 | - | expression tag |
Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 43935.8 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 794.9 | |
All* | Total formula weight | 44730.7 |