8QDW
NMR2 Structure of KRAS G12V (GMPPNP bound) in complex with N-methyl-1-(1-phenylpyrazol-4-yl)methanamine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | RASK GTPase (Fragment) | polymer | 169 | 19297.8 | 1 | UniProt (A0A7L2RV33) Pfam (PF00071) | Homo sapiens (human) | |
| 2 | B (A) | N-methyl-1-(1-phenyl-1H-pyrazol-4-yl)methanamine | non-polymer | 187.2 | 1 | Chemie (W1Y) |
Sequence modifications
A: 1 - 169 (UniProt: A0A7L2RV33)
| PDB | External Database | Details |
|---|---|---|
| Val 12 | Gly 12 | engineered mutation |
| Ser 118 | Cys 118 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 19297.8 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 187.2 | |
| All* | Total formula weight | 19485.0 |
