8Q7B
ABCG2 in complex with MZ29 and 5D3 Fab
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C (D, F) | 5D3(Fab) heavy chain variable domain | polymer | 221 | 23843.6 | 2 | Mus musculus | ||
2 | B, F (E, C) | 5D3(Fab) light chain variable domain | polymer | 214 | 23594.0 | 2 | Mus musculus | ||
3 | D, E (B, A) | ATP-binding cassette sub-family G member 2 | polymer | 655 | 72385.9 | 2 | UniProt (Q9UNQ0) Pfam (PF00005) Pfam (PF19055) Pfam (PF01061) | Homo sapiens (human) | Breast cancer resistance protein,CDw338,Mitoxantrone resistance-associated protein,Placenta-specific ATP-binding cassette transporter,Urate exporter |
4 | G, H (G, H) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
5 | I, J, K, L, M... (B, A) | CHOLESTEROL | non-polymer | 386.7 | 10 | Chemie (CLR) | |||
6 | N, O (B, A) | ~{tert}-butyl 3-[(2~{S},5~{S},8~{S})-14-cyclopentyloxy-2-(2-methylpropyl)-4,7-bis(oxidanylidene)-3,6,17-triazatetracyclo[8.7.0.0^{3,8}.0^{11,16}]heptadeca-1(10),11,13,15-tetraen-5-yl]propanoate | non-polymer | 523.7 | 2 | Chemie (BWQ) | |||
7 | U, V, W, X (E, B, A, C) | water | water | 18.0 | 48 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 239647.0 | |
Branched | Number of molecules | 2 |
Total formula weight | 848.8 | |
Non-Polymers* | Number of molecules | 12 |
Total formula weight | 4913.9 | |
All* | Total formula weight | 245409.7 |