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8Q7B

ABCG2 in complex with MZ29 and 5D3 Fab

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, C
(D, F)
5D3(Fab) heavy chain variable domainpolymer22123843.62Mus musculus
2B, F
(E, C)
5D3(Fab) light chain variable domainpolymer21423594.02Mus musculus
3D, E
(B, A)
ATP-binding cassette sub-family G member 2polymer65572385.92UniProt (Q9UNQ0)
Pfam (PF00005)
Pfam (PF19055)
Pfam (PF01061)
Homo sapiens (human)Breast cancer resistance protein,CDw338,Mitoxantrone resistance-associated protein,Placenta-specific ATP-binding cassette transporter,Urate exporter
4G, H
(G, H)
2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched424.42In PDB
GlyTouCan (G42666HT)
5I, J, K, L, M...
(B, A)
CHOLESTEROLnon-polymer386.710Chemie (CLR)
6N, O
(B, A)
~{tert}-butyl 3-[(2~{S},5~{S},8~{S})-14-cyclopentyloxy-2-(2-methylpropyl)-4,7-bis(oxidanylidene)-3,6,17-triazatetracyclo[8.7.0.0^{3,8}.0^{11,16}]heptadeca-1(10),11,13,15-tetraen-5-yl]propanoatenon-polymer523.72Chemie (BWQ)
7U, V, W, X
(E, B, A, C)
waterwater18.048Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains6
Total formula weight239647.0
BranchedNumber of molecules2
Total formula weight848.8
Non-Polymers*Number of molecules12
Total formula weight4913.9
All*Total formula weight245409.7
*Water molecules are not included.

239149

PDB entries from 2025-07-23

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