8Q6J
Atomic structure and conformational variability of the HER2-Trastuzumab-Pertuzumab complex
This is a non-PDB format compatible entry.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Trastuzumab fab light chain | polymer | 214 | 23466.0 | 1 | Homo sapiens | ||
2 | B | Trastuzumab Fab heavy chain | polymer | 220 | 23425.2 | 1 | Homo sapiens | ||
3 | C | Pertuzumab Fab light chain | polymer | 214 | 23548.2 | 1 | Homo sapiens | ||
4 | D | Pertuzumab Fab heavy chain | polymer | 222 | 23674.5 | 1 | Homo sapiens | ||
5 | E | Receptor tyrosine-protein kinase erbB-2 | polymer | 624 | 68794.1 | 1 | UniProt (P04626) Pfam (PF01030) Pfam (PF00757) Pfam (PF14843) In PDB | Homo sapiens (human) | |
6 | G, J | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 2 | In PDB GlyTouCan (G15407YE) | |||
7 | E | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 3 | Chemie (NAG) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 5 |
Total formula weight | 162907.9 | |
Branched | Number of molecules | 2 |
Total formula weight | 1173.1 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 663.6 | |
All* | Total formula weight | 164744.6 |