8Q5C
Ternary structure of 14-3-3s, C-RAF phosphopeptide (pS259) and compound 12 (1075475)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 14-3-3 protein sigma | polymer | 236 | 26542.9 | 1 | UniProt (P31947) Pfam (PF00244) | Homo sapiens (human) | Epithelial cell marker protein 1,Stratifin |
| 2 | B (P) | C-RAF peptide pS259 | polymer | 10 | 1208.2 | 1 | UniProt (by SIFTS) (P04049) | Homo sapiens | |
| 3 | C (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 4 | D, E, F, H (A) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 5 | G (A) | ~{N}-[[1-(4-chlorophenyl)sulfonylpiperidin-4-yl]methyl]ethanamide | non-polymer | 330.8 | 1 | Chemie (W5T) | |||
| 6 | I, J (A, P) | water | water | 18.0 | 128 | Chemie (HOH) |
Sequence modifications
A: 1 - 231 (UniProt: P31947)
| PDB | External Database | Details |
|---|---|---|
| Gly -4 | - | expression tag |
| Ala -3 | - | expression tag |
| Met -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 27751.1 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 463.5 | |
| All* | Total formula weight | 28214.6 |
