8Q4W
Crystal structure of YTHDC1 in complex with Compound 40 (CS_3a)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | YTH domain-containing protein 1 | polymer | 166 | 18823.8 | 2 | UniProt (Q96MU7) Pfam (PF04146) | Homo sapiens (human) | Splicing factor YT521,YT521-B |
| 2 | C, F (A, B) | 5-chloranyl-3-[(3-chlorophenyl)methyl]-~{N}-methyl-2~{H}-pyrazolo[4,3-d]pyrimidin-7-amine | non-polymer | 308.2 | 2 | Chemie (JNC) | |||
| 3 | D, E, G, H, I (A, B) | SULFATE ION | non-polymer | 96.1 | 5 | Chemie (SO4) | |||
| 4 | J, K (A, B) | water | water | 18.0 | 198 | Chemie (HOH) |
Sequence modifications
A, B: 345 - 509 (UniProt: Q96MU7)
| PDB | External Database | Details |
|---|---|---|
| Gly 344 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 37647.7 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1096.6 | |
| All* | Total formula weight | 38744.3 |
