8Q42
Crystal structure of cA4-bound Can2 (E341A) in complex with oligo-A DNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | DUF1887 family protein | polymer | 439 | 51342.4 | 2 | UniProt (E8URK0) | Thermoanaerobacter brockii subsp. finnii Ako-1 | |
| 2 | C (D) | DNA (5'-D(*AP*AP*AP*A)-3') | polymer | 6 | 1834.3 | 1 | Thermoanaerobacter brockii subsp. finnii Ako-1 | ||
| 3 | D (X) | Cyclic tetraadenosine monophosphate (cA4) | polymer | 4 | 1271.9 | 1 | BIRD (PRD_002431) | synthetic construct | |
| 4 | E, F (A, B) | MANGANESE (II) ION | non-polymer | 54.9 | 2 | Chemie (MN) | |||
| 5 | G, H, I, J (A, B, D, X) | water | water | 18.0 | 263 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 437 (UniProt: E8URK0)
| PDB | External Database | Details |
|---|---|---|
| Ser -1 | - | expression tag |
| Asn 0 | - | expression tag |
| Ala 341 | Glu 341 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 105791.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 109.9 | |
| All* | Total formula weight | 105900.9 |
