8Q41
Crystal structure of Can2 (E341A) bound to cA4 and TTTAAA ssDNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | DUF1887 family protein | polymer | 439 | 51342.4 | 2 | UniProt (E8URK0) | Thermoanaerobacter brockii subsp. finnii Ako-1 | |
| 2 | C, D (D, C) | DNA (5'-D(*TP*TP*AP*AP*A)-3') | polymer | 6 | 1807.2 | 2 | Thermoanaerobacter brockii subsp. finnii Ako-1 | ||
| 3 | E (X) | Cyclic tetraadenosine monophosphate (cA4) | polymer | 4 | 1271.9 | 1 | BIRD (PRD_002431) | synthetic construct | |
| 4 | F, G, H (A, B) | MANGANESE (II) ION | non-polymer | 54.9 | 3 | Chemie (MN) | |||
| 5 | I, J, K, L, M (A, B, D, C, X) | water | water | 18.0 | 154 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 437 (UniProt: E8URK0)
| PDB | External Database | Details |
|---|---|---|
| Ser -1 | - | expression tag |
| Asn 0 | - | expression tag |
| Ala 341 | Glu 341 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 107571.2 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 164.8 | |
| All* | Total formula weight | 107736.0 |
