8Q3R
Cryo-EM structure of the DNA polymerase holoenzyme E9-A20-D4 of vaccinia virus
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (D) | Uracil-DNA glycosylase | polymer | 242 | 27468.4 | 1 | UniProt (P20536) | Vaccinia virus Copenhagen | |
| 2 | B (A) | DNA polymerase processivity factor component OPG148 | polymer | 426 | 49247.0 | 1 | UniProt (P20995) Pfam (PF05941) | Vaccinia virus Copenhagen | |
| 3 | C (E) | DNA polymerase | polymer | 1033 | 120361.5 | 1 | UniProt (P20509) Pfam (PF08452) Pfam (PF03104) Pfam (PF08408) Pfam (PF00136) | Vaccinia virus Copenhagen |
Sequence modifications
D: 1 - 218 (UniProt: P20536)
E: 2 - 1006 (UniProt: P20509)
| PDB | External Database | Details |
|---|---|---|
| Met -23 | - | initiating methionine |
| Ala -22 | - | expression tag |
| Ser -21 | - | expression tag |
| Trp -20 | - | expression tag |
| Ser -19 | - | expression tag |
| His -18 | - | expression tag |
| Pro -17 | - | expression tag |
| Gln -16 | - | expression tag |
| Phe -15 | - | expression tag |
| Glu -14 | - | expression tag |
| Lys -13 | - | expression tag |
| Ser -12 | - | expression tag |
| Gly -11 | - | expression tag |
| Gly -10 | - | expression tag |
| Gly -9 | - | expression tag |
| Gly -8 | - | expression tag |
| Gly -7 | - | expression tag |
| Leu -6 | - | expression tag |
| Val -5 | - | expression tag |
| Pro -4 | - | expression tag |
| Arg -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| Ala 0 | - | expression tag |
| Ala 208 | Val 208 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Met -26 | - | initiating methionine |
| Ser -25 | - | expression tag |
| Tyr -24 | - | expression tag |
| Tyr -23 | - | expression tag |
| His -22 | - | expression tag |
| His -21 | - | expression tag |
| His -20 | - | expression tag |
| His -19 | - | expression tag |
| His -18 | - | expression tag |
| His -17 | - | expression tag |
| Asp -16 | - | expression tag |
| Tyr -15 | - | expression tag |
| Asp -14 | - | expression tag |
| Ile -13 | - | expression tag |
| Pro -12 | - | expression tag |
| Thr -11 | - | expression tag |
| Thr -10 | - | expression tag |
| Glu -9 | - | expression tag |
| Asn -8 | - | expression tag |
| Leu -7 | - | expression tag |
| Tyr -6 | - | expression tag |
| Phe -5 | - | expression tag |
| Gln -4 | - | expression tag |
| Gly -3 | - | expression tag |
| Ala -2 | - | expression tag |
| Met -1 | - | expression tag |
| Asp 0 | - | expression tag |
| Pro 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 197076.9 | |
| All* | Total formula weight | 197076.9 |
