8Q2V
Crystal structure of YTHDC1 in complex with Compound 7 (ZA_560)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | YTH domain-containing protein 1 | polymer | 166 | 18823.8 | 2 | UniProt (Q96MU7) Pfam (PF04146) | Homo sapiens (human) | Splicing factor YT521,YT521-B |
| 2 | C, F (A, B) | 2-chloranyl-~{N}-methyl-9-[(2~{S})-oxan-2-yl]purin-6-amine | non-polymer | 267.7 | 2 | Chemie (IUQ) | |||
| 3 | D, E, G, H (A, B) | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 4 | I, J (A, B) | water | water | 18.0 | 202 | Chemie (HOH) |
Sequence modifications
A, B: 345 - 509 (UniProt: Q96MU7)
| PDB | External Database | Details |
|---|---|---|
| Gly 344 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 37647.7 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 919.7 | |
| All* | Total formula weight | 38567.3 |
