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8PYJ

Human IGF1R with inhibitor 8

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(AAA)
Insulin-like growth factor 1 receptor beta chainpolymer32136716.01UniProt (P08069)
Pfam (PF07714)
Homo sapiens (human)
2B
(AAA)
5,5-dimethyl-1-(quinolin-4-ylmethyl)-3-[4-(trifluoromethylsulfonyl)phenyl]imidazolidine-2,4-dionenon-polymer477.51Chemie (IEA)
3C
(AAA)
NICKEL (II) IONnon-polymer58.71Chemie (NI)
4D
(AAA)
CADMIUM IONnon-polymer112.41Chemie (CD)
5E
(AAA)
ZINC IONnon-polymer65.41Chemie (ZN)
6F
(AAA)
waterwater18.045Chemie (HOH)
Sequence modifications
AAA: 974 - 1286 (UniProt: P08069)
PDBExternal DatabaseDetails
Met 973-initiating methionine
Ala 1287-expression tag
Glu 1288-expression tag
Asn 1289-expression tag
Leu 1290-expression tag
Tyr 1291-expression tag
Phe 1292-expression tag
Gln 1293-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight36716.0
Non-Polymers*Number of molecules4
Total formula weight714.0
All*Total formula weight37430.0
*Water molecules are not included.

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PDB entries from 2024-11-13

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