8PXY
Crystal structure of the transpeptidase LdtMt2 C354S mutant from Mycobacterium tuberculosis in complex with natural substrate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | L,D-transpeptidase 2 | polymer | 355 | 37993.1 | 1 | UniProt (O53223) Pfam (PF17964) Pfam (PF03734) UniProt (by SIFTS) (I6Y9J2) | Mycobacterium tuberculosis | LDT 2,Ldt(Mt2) |
| 2 | B (B) | Peptidoglycan tetrapeptide | polymer | 4 | 459.5 | 1 | BIRD (PRD_002583) | Corynebacterium jeikeium | |
| 3 | C (C) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-N-acetyl-alpha-muramic acid | branched | 496.5 | 1 | In PDB BIRD (PRD_002583) GlyTouCan (G88499BX) | |||
| 4 | D (A) | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | non-polymer | 238.3 | 1 | Chemie (EPE) | |||
| 5 | E (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 6 | F, G (A, B) | water | water | 18.0 | 337 | Chemie (HOH) |
Sequence modifications
A: 56 - 408 (UniProt: O53223)
| PDB | External Database | Details |
|---|---|---|
| Gln 54 | - | expression tag |
| Ser 55 | - | expression tag |
| Ser 354 | Cys 354 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 38452.6 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 496.5 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 273.8 | |
| All* | Total formula weight | 39222.8 |
