8PWN

Structure of A2A adenosine receptor A2AR-StaR2-bRIL, solved at wavelength 2.75 A

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Adenosine receptor A2a,Soluble cytochrome b562	polymer	433	47996.7	1	UniProt (P29274) UniProt (P0ABE7) Pfam (PF00001) Pfam (PF07361) In PDB	Homo sapiens (human)
2	A	THEOPHYLLINE	non-polymer		180.2	1	Chemie (TEP)
3	A	OLEIC ACID	non-polymer		282.5	12	Chemie (OLA)
4	A	CHOLESTEROL	non-polymer		386.7	3	Chemie (CLR)
5		water	water		18.0	26	Chemie (HOH)

Sequence modifications

A: 27 - 233 (UniProt: P29274)

PDB	External Database	Details
Asp 17	-	expression tag
Tyr 18	-	expression tag
Lys 19	-	expression tag
Asp 20	-	expression tag
Asp 21	-	expression tag
Asp 22	-	expression tag
Asp 23	-	expression tag
Gly 24	-	expression tag
Ala 25	-	expression tag
Pro 26	-	expression tag
Leu 79	Ala 54	conflict
Ala 113	Thr 88	conflict
Ala 132	Arg 107	conflict
Ala 147	Lys 122	conflict
Ala 179	Asn 154	conflict
Ala 227	Leu 202	conflict

A: 234 - 334 (UniProt: P0ABE7)

PDB	External Database	Details
Trp 240	Met 29	conflict
Ile 335	-	linker
Gln 336	-	linker
Lys 337	-	linker
Tyr 338	-	linker
Leu 339	-	linker

A: 340 - 439 (UniProt: P29274)

PDB	External Database	Details
Ala 356	Leu 235	conflict
Ala 360	Val 239	conflict
Ala 398	Ser 277	conflict
Ala 439	Gly 318	conflict
His 440	-	expression tag
His 441	-	expression tag
His 442	-	expression tag
His 443	-	expression tag
His 444	-	expression tag
His 445	-	expression tag
His 446	-	expression tag
His 447	-	expression tag
His 448	-	expression tag
His 449	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	47996.7
Non-Polymers*	Number of molecules	16
	Total formula weight	4729.7
All*	Total formula weight	52726.4

*Water molecules are not included.