8PWM
Crystal structure of VDR in complex with Des-C-Ring and Aromatic-D-Ring analog 3b
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Vitamin D3 receptor A | polymer | 302 | 34060.7 | 1 | UniProt (Q9PTN2) Pfam (PF00104) In PDB | Danio rerio (zebrafish) | VDR-A,1,25-dihydroxyvitamin D3 receptor A,Nuclear receptor subfamily 1 group I member 1-A |
2 | B | Nuclear receptor coactivator 2 | polymer | 13 | 1579.9 | 1 | UniProt (Q15596) In PDB | Homo sapiens | NCoA-2,Class E basic helix-loop-helix protein 75,bHLHe75,Transcriptional intermediary factor 2,hTIF2 |
3 | A | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
4 | A | (1R,3S,5Z)-4-methylidene-5-[(E)-3-[3-[7,7,7-tris(fluoranyl)-6-oxidanyl-6-(trifluoromethyl)hept-3-ynyl]phenyl]but-2-enylidene]cyclohexane-1,3-diol | non-polymer | 488.5 | 1 | Chemie (HXI) | |||
5 | water | water | 18.0 | 47 | Chemie (HOH) |
Sequence modifications
A: 156 - 453 (UniProt: Q9PTN2)
PDB | External Database | Details |
---|---|---|
Gly 152 | - | expression tag |
Ser 153 | - | expression tag |
His 154 | - | expression tag |
Met 155 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 35640.5 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 547.5 | |
All* | Total formula weight | 36188.0 |