8PVU
Cryo-EM structure of DHS-ERK2 complex with 1:1 stoichiometry refined in C1 symmetry
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (E) | Mitogen-activated protein kinase 1 | polymer | 361 | 41531.7 | 1 | UniProt (P28482) Pfam (PF00069) | Homo sapiens (human) | MAP kinase 1,MAPK 1,ERT1,Extracellular signal-regulated kinase 2,ERK-2,MAP kinase isoform p42,p42-MAPK,Mitogen-activated protein kinase 2,MAP kinase 2,MAPK 2 |
| 2 | B, C, D, E (A, B, C, D) | Deoxyhypusine synthase | polymer | 370 | 41099.5 | 4 | UniProt (P49366) Pfam (PF01916) | Homo sapiens (human) | DHS |
Sequence modifications
E: 1 - 360 (UniProt: P28482)
A, B, C, D: 1 - 369 (UniProt: P49366)
| PDB | External Database | Details |
|---|---|---|
| Ser 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 205929.8 | |
| All* | Total formula weight | 205929.8 |
