8PVR
Cryo-EM structure of horse Nhe9 bound to PI(3,5)P2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (B, A) | Sodium/hydrogen exchanger 9 | polymer | 574 | 64856.1 | 2 | UniProt (F7B113) Pfam (PF00999) | Equus caballus (horse) | Na(+)/H(+) exchanger 9,NHE-9,Sodium/hydrogen exchanger,Solute carrier family 9 member 9 |
| 2 | C, D (B, A) | (2R)-3-{[(S)-hydroxy{[(1S,2R,3R,4S,5S,6R)-2,4,6-trihydroxy-3,5-bis(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dioctanoate | non-polymer | 746.6 | 2 | Chemie (EUJ) |
Sequence modifications
B, A: 8 - 574 (UniProt: F7B113)
| PDB | External Database | Details |
|---|---|---|
| Cys 139 | Leu 139 | engineered mutation |
| Cys 444 | Ile 444 | engineered mutation |
| Gly 575 | - | expression tag |
| Glu 576 | - | expression tag |
| Asn 577 | - | expression tag |
| Leu 578 | - | expression tag |
| Tyr 579 | - | expression tag |
| Phe 580 | - | expression tag |
| Gln 581 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 129712.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1493.1 | |
| All* | Total formula weight | 131205.2 |
