8PVH

Structure of human apo ALDH1A1 determined by cryoEM at 100 keV

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Aldehyde dehydrogenase 1A1	polymer	528	57993.0	1	UniProt (P00352) Pfam (PF00171)	Homo sapiens (human)	3-deoxyglucosone dehydrogenase,ALDH-E1,ALHDII,Aldehyde dehydrogenase family 1 member A1,Aldehyde dehydrogenase,cytosolic,Retinal dehydrogenase 1,RALDH 1,RalDH1
2	B (A)	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL)

Sequence modifications

A: 2 - 501 (UniProt: P00352)

PDB	External Database	Details
Met -26	-	initiating methionine
Ser -25	-	expression tag
Tyr -24	-	expression tag
Tyr -23	-	expression tag
His -22	-	expression tag
His -21	-	expression tag
His -20	-	expression tag
His -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
Leu -16	-	expression tag
Glu -15	-	expression tag
Ser -14	-	expression tag
Thr -13	-	expression tag
Ser -12	-	expression tag
Leu -11	-	expression tag
Tyr -10	-	expression tag
Lys -9	-	expression tag
Lys -8	-	expression tag
Ala -7	-	expression tag
Gly -6	-	expression tag
Ser -5	-	expression tag
Ala -4	-	expression tag
Ala -3	-	expression tag
Ala -2	-	expression tag
Pro -1	-	expression tag
Phe 0	-	expression tag
Thr 1	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	57993.0
Non-Polymers*	Number of molecules	1
	Total formula weight	35.5
All*	Total formula weight	58028.4

*Water molecules are not included.