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8PQ5

Human Cohesin ATPase module with an open DNA exit gate

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Structural maintenance of chromosomes protein 1Apolymer45651443.21UniProt (by SIFTS) (Q14683)Homo sapiens (human)
2B
(B)
Structural maintenance of chromosomes protein 3polymer46252391.41Pfam (PF02463)
UniProt (by SIFTS) (Q9UQE7)
Homo sapiens (human)
3C
(C)
64-kDa C-terminal productpolymer819203.61UniProt (O60216)
Pfam (PF04824)
Homo sapiens (human)64-kDa carboxy-terminal product,65-kDa carboxy-terminal product
4D, E
(A, B)
ADENOSINE-5'-TRIPHOSPHATEnon-polymer507.22Chemie (ATP)
Sequence modifications
C: 558 - 629 (UniProt: O60216)
PDBExternal DatabaseDetails
Met 557-initiating methionine
Gly 630-expression tag
Ser 631-expression tag
Leu 632-expression tag
Glu 633-expression tag
Val 634-expression tag
Leu 635-expression tag
Phe 636-expression tag
Gln 637-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight113038.3
Non-Polymers*Number of molecules2
Total formula weight1014.4
All*Total formula weight114052.6
*Water molecules are not included.

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PDB entries from 2025-06-11

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