8POM

TEAD2 in complex with an inhibitor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (B, A)	Transcriptional enhancer factor TEF-4	polymer	240	27489.1	2	UniProt (Q15562) Pfam (PF17725)	Homo sapiens (human)	TEA domain family member 2,TEAD-2
2	C, E (B, A)	2-[[3-(2-phenylethoxy)phenyl]amino]pyridine-3-carboxylic acid	non-polymer		334.4	2	Chemie (ZUP)
3	D (B)	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
4	F, G (B, A)	water	water		18.0	43	Chemie (HOH)

Sequence modifications

B, A: 217 - 447 (UniProt: Q15562)

PDB	External Database	Details
Met 216	-	initiating methionine
Val 448	-	expression tag
Glu 449	-	expression tag
His 450	-	expression tag
His 451	-	expression tag
His 452	-	expression tag
His 453	-	expression tag
His 454	-	expression tag
His 455	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	54978.2
Non-Polymers*	Number of molecules	3
	Total formula weight	760.8
All*	Total formula weight	55739.0

*Water molecules are not included.