8POM
TEAD2 in complex with an inhibitor
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | B, A | Transcriptional enhancer factor TEF-4 | polymer | 240 | 27489.1 | 2 | UniProt (Q15562) Pfam (PF17725) In PDB | Homo sapiens (human) | TEA domain family member 2,TEAD-2 |
2 | B, A | 2-[[3-(2-phenylethoxy)phenyl]amino]pyridine-3-carboxylic acid | non-polymer | 334.4 | 2 | Chemie (ZUP) | |||
3 | B | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
4 | water | water | 18.0 | 43 | Chemie (HOH) |
Sequence modifications
B, A: 217 - 447 (UniProt: Q15562)
PDB | External Database | Details |
---|---|---|
Met 216 | - | initiating methionine |
Val 448 | - | expression tag |
Glu 449 | - | expression tag |
His 450 | - | expression tag |
His 451 | - | expression tag |
His 452 | - | expression tag |
His 453 | - | expression tag |
His 454 | - | expression tag |
His 455 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 54978.2 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 760.8 | |
All* | Total formula weight | 55739.0 |