8PKN
CryoEM structure of catalytic domain of human HMG-CoA reductase with its inhibitor atorvastatin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | polymer | 423 | 45259.0 | 1 | UniProt (P04035) Pfam (PF00368) | Homo sapiens (human) | HMG-CoA reductase |
| 2 | B (A) | 7-[2-(4-FLUORO-PHENYL)-5-ISOPROPYL-3-PHENYL-4-PHENYLCARBAMOYL-PYRROL-1-YL]- 3,5-DIHYDROXY-HEPTANOIC ACID | non-polymer | 558.6 | 1 | Chemie (117) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 45259.0 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 558.6 | |
| All* | Total formula weight | 45817.7 |
