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8PK0

human mitoribosomal large subunit assembly intermediate 1 with GTPBP10-GTPBP7

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1039S ribosomal protein L32, mitochondrialpolymer18821437.81UniProt (Q9BYC8)
Pfam (PF01783)
In PDB
Homo sapiens (human)L32mt,MRP-L32,Mitochondrial large ribosomal subunit protein bL32m
2T39S ribosomal protein L22, mitochondrialpolymer20623683.71UniProt (Q9NWU5)
Pfam (PF00237)
In PDB
Homo sapiens (human)L22mt,MRP-L22,39S ribosomal protein L25,mitochondrial,L25mt,MRP-L25,Mitochondrial large ribosomal subunit protein uL22m
3uMitochondrial assembly of ribosomal large subunit protein 1polymer23426203.11UniProt (Q96EH3)
Pfam (PF02410)
In PDB
Homo sapiens (human)
4139S ribosomal protein L33, mitochondrialpolymer657635.21UniProt (O75394)
Pfam (PF00471)
In PDB
Homo sapiens (human)L33mt,MRP-L33,Mitochondrial large ribosomal subunit protein bL33m
5U39S ribosomal protein L23, mitochondrialpolymer15317849.21UniProt (Q16540)
Pfam (PF00276)
In PDB
Homo sapiens (human)L23mt,MRP-L23,L23 mitochondrial-related protein,Mitochondrial large ribosomal subunit protein uL23m,Ribosomal protein L23-like
6vMIEF1 upstream open reading frame proteinpolymer708460.81UniProt (L0R8F8)
Pfam (PF05347)
In PDB
Homo sapiens (human)
7239S ribosomal protein L34, mitochondrialpolymer9210183.91UniProt (Q9BQ48)
Pfam (PF00468)
In PDB
Homo sapiens (human)L34mt,MRP-L34,Mitochondrial large ribosomal subunit protein bL34m
8V39S ribosomal protein L24, mitochondrialpolymer21624953.91UniProt (Q96A35)
Pfam (PF00467)
Pfam (PF17136)
In PDB
Homo sapiens (human)L24mt,MRP-L24,Mitochondrial large ribosomal subunit protein uL24m
9wAcyl carrier protein, mitochondrialpolymer15617434.31UniProt (O14561)
Pfam (PF00550)
In PDB
Homo sapiens (human)ACP,CI-SDAP,NADH-ubiquinone oxidoreductase 9.6 kDa subunit
10339S ribosomal protein L35, mitochondrialpolymer18821558.51UniProt (Q9NZE8)
Pfam (PF01632)
In PDB
Homo sapiens (human)L35mt,MRP-L35,Mitochondrial large ribosomal subunit protein bL35m
11W39S ribosomal protein L27, mitochondrialpolymer14816102.91UniProt (Q9P0M9)
Pfam (PF01016)
In PDB
Homo sapiens (human)L27mt,MRP-L27,Mitochondrial large ribosomal subunit protein bL27m
12x5-methylcytosine rRNA methyltransferase NSUN4polymer38443140.51UniProt (Q96CB9)
Pfam (PF01189)
In PDB
Homo sapiens (human)NOL1/NOP2/Sun domain family member 4
13539S ribosomal protein L37, mitochondrialpolymer42348183.31UniProt (Q9BZE1)
Pfam (PF07147)
In PDB
Homo sapiens (human)L37mt,MRP-L37,39S ribosomal protein L2,mitochondrial,L2mt,MRP-L2,Mitochondrial large ribosomal subunit protein mL37
14X39S ribosomal protein L28, mitochondrialpolymer25630202.91UniProt (Q13084)
Pfam (PF00830)
In PDB
Homo sapiens (human)L28mt,MRP-L28,Melanoma antigen p15,Melanoma-associated antigen recognized by T-lymphocytes,Mitochondrial large ribosomal subunit protein bL28m
15yTranscription termination factor 4, mitochondrialpolymer38144012.51UniProt (Q7Z6M4)
Pfam (PF02536)
In PDB
Homo sapiens (human)Mitochondrial transcription termination factor 4,mTERF domain-containing protein 2
16639S ribosomal protein L38, mitochondrialpolymer38044659.41UniProt (Q96DV4)
Pfam (PF01161)
In PDB
Homo sapiens (human)L38mt,MRP-L38,Mitochondrial large ribosomal subunit protein mL38
17Y39S ribosomal protein L47, mitochondrialpolymer25029508.51UniProt (Q9HD33)
Pfam (PF06984)
In PDB
Homo sapiens (human)L47mt,MRP-L47,Mitochondrial large ribosomal subunit protein uL29m,Nasopharyngeal carcinoma metastasis-related protein 1
18zMitochondrial ribosome-associated GTPase 1polymer33437292.71UniProt (Q9BT17)
Pfam (PF01926)
In PDB
Homo sapiens (human)GTP-binding protein 7,Mitochondrial GTPase 1
19739S ribosomal protein L39, mitochondrialpolymer33838764.81UniProt (Q9NYK5)
In PDB
Homo sapiens (human)L39mt,MRP-L39,39S ribosomal protein L5,mitochondrial,L5mt,MRP-L5,Mitochondrial large ribosomal subunit protein mL39
20Z39S ribosomal protein L30, mitochondrialpolymer16118582.81UniProt (Q8TCC3)
Pfam (PF00327)
In PDB
Homo sapiens (human)L30mt,MRP-L30,39S ribosomal protein L28,mitochondrial,L28mt,MRP-L28,Mitochondrial large ribosomal subunit protein uL30m
21839S ribosomal protein L40, mitochondrialpolymer20624534.41UniProt (Q9NQ50)
Pfam (PF09812)
In PDB
Homo sapiens (human)L40mt,MRP-L40,Mitochondrial large ribosomal subunit protein mL40,Nuclear localization signal-containing protein deleted in velocardiofacial syndrome,Up-regulated in metastasis
22a39S ribosomal protein L42, mitochondrialpolymer14216691.21UniProt (Q9Y6G3)
Pfam (PF10210)
In PDB
Homo sapiens (human)L42mt,MRP-L42,39S ribosomal protein L31,mitochondrial,L31mt,MRP-L31,Mitochondrial large ribosomal subunit protein mL42
23939S ribosomal protein L41, mitochondrialpolymer13715404.71UniProt (Q8IXM3)
Pfam (PF09809)
In PDB
Homo sapiens (human)L41mt,MRP-L41,39S ribosomal protein L27 homolog,Bcl-2-interacting mitochondrial ribosomal protein L41,Cell proliferation-inducing gene 3 protein,MRP-L27 homolog,Mitochondrial large ribosomal subunit protein mL41
24bLarge ribosomal subunit protein mL43polymer21523352.61UniProt (Q8N983)
Pfam (PF05047)
In PDB
Homo sapiens (human)39S ribosomal protein L43,mitochondrial,L43mt,MRP-L43,Mitochondrial ribosomal protein bMRP36a
25A16S rRNA + pre-H68-71 segmentpolymer1589509550.61GenBank (1858624182)Homo sapiens (human)
26c39S ribosomal protein L44, mitochondrialpolymer33237583.31UniProt (Q9H9J2)
Pfam (PF22935)
Pfam (PF22892)
In PDB
Homo sapiens (human)L44mt,MRP-L44,Mitochondrial large ribosomal subunit protein mL44
27BCP tRNA-Valpolymer7222961.71GenBank (1896813692)Homo sapiens (human)
28d39S ribosomal protein L45, mitochondrialpolymer30635402.91UniProt (Q9BRJ2)
Pfam (PF04280)
In PDB
Homo sapiens (human)L45mt,MRP-L45,Mitochondrial large ribosomal subunit protein mL45
29D39S ribosomal protein L2, mitochondrialpolymer30533355.91UniProt (Q5T653)
Pfam (PF03947)
Pfam (PF00181)
In PDB
Homo sapiens (human)L2mt,MRP-L2,Mitochondrial large ribosomal subunit protein uL2m
30e39S ribosomal protein L46, mitochondrialpolymer27931748.11UniProt (Q9H2W6)
Pfam (PF11788)
In PDB
Homo sapiens (human)L46mt,MRP-L46,Mitochondrial large ribosomal subunit protein mL46,P2ECSL
31E39S ribosomal protein L3, mitochondrialpolymer34838689.61UniProt (P09001)
Pfam (PF00297)
In PDB
Homo sapiens (human)L3mt,MRP-L3,Mitochondrial large ribosomal subunit protein uL3m
32f39S ribosomal protein L48, mitochondrialpolymer21223970.81UniProt (Q96GC5)
Pfam (PF00338)
In PDB
Homo sapiens (human)L48mt,MRP-L48,Mitochondrial large ribosomal subunit protein mL48
33F39S ribosomal protein L4, mitochondrialpolymer31134970.21UniProt (Q9BYD3)
Pfam (PF00573)
In PDB
Homo sapiens (human)L4mt,MRP-L4,Mitochondrial large ribosomal subunit protein uL4m
34g39S ribosomal protein L49, mitochondrialpolymer16619225.01UniProt (Q13405)
Pfam (PF05046)
In PDB
Homo sapiens (human)L49mt,MRP-L49,Mitochondrial large ribosomal subunit protein mL49,Neighbor of FAU,NOF,Protein NOF1
35H39S ribosomal protein L9, mitochondrialpolymer26730296.41UniProt (Q9BYD2)
Pfam (PF01281)
Pfam (PF22078)
In PDB
Homo sapiens (human)L9mt,MRP-L9,Mitochondrial large ribosomal subunit protein bL9m
36h39S ribosomal protein L50, mitochondrialpolymer15818349.91UniProt (Q8N5N7)
Pfam (PF10501)
In PDB
Homo sapiens (human)L50mt,MRP-L50,Mitochondrial large ribosomal subunit protein mL50
37I39S ribosomal protein L10, mitochondrialpolymer26129322.51UniProt (Q7Z7H8)
Pfam (PF00466)
In PDB
Homo sapiens (human)L10mt,MRP-L10,39S ribosomal protein L8,mitochondrial,L8mt,MRP-L8,Mitochondrial large ribosomal subunit protein uL10m
38i39S ribosomal protein L51, mitochondrialpolymer12815125.91UniProt (Q4U2R6)
Pfam (PF10244)
In PDB
Homo sapiens (human)L51mt,MRP-L51,Mitochondrial large ribosomal subunit protein mL51,bMRP-64,bMRP64
39J39S ribosomal protein L11, mitochondrialpolymer19220716.21UniProt (Q9Y3B7)
Pfam (PF03946)
Pfam (PF00298)
In PDB
Homo sapiens (human)L11mt,MRP-L11,Mitochondrial large ribosomal subunit protein uL11m
40j39S ribosomal protein L52, mitochondrialpolymer12313682.71UniProt (Q86TS9)
Pfam (PF18699)
In PDB
Homo sapiens (human)L52mt,MRP-L52,Mitochondrial large ribosomal subunit protein mL52
41K39S ribosomal protein L13, mitochondrialpolymer17820765.01UniProt (Q9BYD1)
Pfam (PF00572)
In PDB
Homo sapiens (human)L13mt,MRP-L13,Mitochondrial large ribosomal subunit protein uL13m
42k39S ribosomal protein L53, mitochondrialpolymer11212167.91UniProt (Q96EL3)
Pfam (PF10780)
In PDB
Homo sapiens (human)L53mt,MRP-L53,Mitochondrial large ribosomal subunit protein mL53
43L39S ribosomal protein L14, mitochondrialpolymer14515973.71UniProt (Q6P1L8)
Pfam (PF00238)
In PDB
Homo sapiens (human)L14mt,MRP-L14,39S ribosomal protein L32,mitochondrial,L32mt,MRP-L32,Mitochondrial large ribosomal subunit protein uL14m
44l39S ribosomal protein L54, mitochondrialpolymer13815844.21UniProt (Q6P161)
Pfam (PF08561)
In PDB
Homo sapiens (human)L54mt,MRP-L54,Mitochondrial large ribosomal subunit protein mL54
45M39S ribosomal protein L15, mitochondrialpolymer29633473.81UniProt (Q9P015)
Pfam (PF00828)
In PDB
Homo sapiens (human)L15mt,MRP-L15,Mitochondrial large ribosomal subunit protein uL15m
46m39S ribosomal protein L55, mitochondrialpolymer12815160.41UniProt (Q7Z7F7)
Pfam (PF09776)
In PDB
Homo sapiens (human)L55mt,MRP-L55,Mitochondrial large ribosomal subunit protein bL31m,Mitochondrial large ribosomal subunit protein mL55
47N39S ribosomal protein L16, mitochondrialpolymer25128496.31UniProt (Q9NX20)
Pfam (PF00252)
In PDB
Homo sapiens (human)L16mt,MRP-L16,Mitochondrial large ribosomal subunit protein uL16m
48oRibosomal protein 63, mitochondrialpolymer10212292.31UniProt (Q9BQC6)
Pfam (PF14978)
In PDB
Homo sapiens (human)hMRP63,Mitochondrial large ribosomal subunit protein mL63,Mitochondrial ribosomal protein 63,Mitochondrial ribosomal protein L57
49O39S ribosomal protein L17, mitochondrialpolymer17520083.31UniProt (Q9NRX2)
Pfam (PF01196)
In PDB
Homo sapiens (human)L17mt,MRP-L17,LYST-interacting protein 2,Mitochondrial large ribosomal subunit protein bL17m
50pPeptidyl-tRNA hydrolase ICT1, mitochondrialpolymer20623674.21UniProt (Q14197)
Pfam (PF00472)
In PDB
Homo sapiens (human)39S ribosomal protein L58,mitochondrial,MRP-L58,Digestion substraction 1,DS-1,Immature colon carcinoma transcript 1 protein,Mitochondrial large ribosomal subunit protein mL62
51P39S ribosomal protein L18, mitochondrialpolymer18020607.61UniProt (Q9H0U6)
Pfam (PF00861)
In PDB
Homo sapiens (human)L18mt,MRP-L18,Mitochondrial large ribosomal subunit protein uL18m
52qGrowth arrest and DNA damage-inducible proteins-interacting protein 1polymer22225426.91UniProt (Q8TAE8)
Pfam (PF10147)
In PDB
Homo sapiens (human)39S ribosomal protein L59,mitochondrial,MRP-L59,CKII beta-associating protein,CR6-interacting factor 1,CRIF1,Mitochondrial large ribosomal subunit protein mL64,Papillomavirus L2-interacting nuclear protein 1,PLINP,PLINP-1,p53-responsive gene 6 protein
53Q39S ribosomal protein L19, mitochondrialpolymer29233585.01UniProt (P49406)
Pfam (PF01245)
In PDB
Homo sapiens (human)L19mt,MRP-L19,39S ribosomal protein L15,mitochondrial,L15mt,MRP-L15,Mitochondrial large ribosomal subunit protein bL19m
54r39S ribosomal protein S18a, mitochondrialpolymer19622224.11UniProt (Q9NVS2)
Pfam (PF01084)
In PDB
Homo sapiens (human)MRP-S18-a,Mrps18a,S18mt-a,39S ribosomal protein S18-3,mitochondrial,MRP-S18-3,Mitochondrial large ribosomal subunit protein bS18a,Mitochondrial large ribosomal subunit protein mL66
55R39S ribosomal protein L20, mitochondrialpolymer14917479.71UniProt (Q9BYC9)
Pfam (PF00453)
In PDB
Homo sapiens (human)L20mt,MRP-L20,Mitochondrial large ribosomal subunit protein bL20m
56s39S ribosomal protein S30, mitochondrialpolymer43950429.61UniProt (Q9NP92)
Pfam (PF07147)
In PDB
Homo sapiens (human)MRP-S30,S30mt,Mitochondrial large ribosomal subunit protein mL65,Mitochondrial large ribosomal subunit protein mS30,Programmed cell death protein 9
57S39S ribosomal protein L21, mitochondrialpolymer20522847.71UniProt (Q7Z2W9)
Pfam (PF00829)
In PDB
Homo sapiens (human)L21mt,MRP-L21,Mitochondrial large ribosomal subunit protein bL21m
58tGTP-binding protein 10polymer38742996.91UniProt (A4D1E9)
Pfam (PF01018)
Pfam (PF01926)
In PDB
Homo sapiens (human)Protein obg homolog 2,ObgH2
590ZINC IONnon-polymer65.41Chemie (ZN)
60wS-(2-{[N-(2-HYDROXY-4-{[HYDROXY(OXIDO)PHOSPHINO]OXY}-3,3-DIMETHYLBUTANOYL)-BETA-ALANYL]AMINO}ETHYL) DECANETHIOATEnon-polymer496.61Chemie (PM8)
61xS-ADENOSYLMETHIONINEnon-polymer398.41Chemie (SAM)
62z, tPHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTERnon-polymer522.22Chemie (GNP)
63A, E, z, g, tMAGNESIUM IONnon-polymer24.396Chemie (MG)
64APOTASSIUM IONnon-polymer39.110Chemie (K)
Sequence modifications
b: 2 - 215 (UniProt: Q8N983)
PDBExternal DatabaseDetails
Ace 2-acetylation
A: 1671 - 2547 (GenBank: 1858624182)
A: 2548 - 2578 (PDB: 8PK0)
A: 2579 - 3259 (GenBank: 1858624182)
PDBExternal DatabaseDetails
A 2737G 2706conflict
U 3138-insertion
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains58
Total formula weight1958313.9
Non-Polymers*Number of molecules111
Total formula weight4729.1
All*Total formula weight1963043.0
*Water molecules are not included.

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PDB entries from 2024-10-09

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