8PIY
NMR2 Structure of KRAS G12V (GMPPNP bound) in complex with (2E)-3-(1H-indol-2-yl)prop-2-enoic acid
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | RASK GTPase (Fragment) | polymer | 169 | 19297.8 | 1 | UniProt (A0A7L2RV33) Pfam (PF00071) In PDB | Homo sapiens (human) | |
2 | A | (~{E})-3-(1~{H}-indol-3-yl)prop-2-enoic acid | non-polymer | 187.2 | 1 | Chemie (Z5I) |
Sequence modifications
A: 1 - 169 (UniProt: A0A7L2RV33)
PDB | External Database | Details |
---|---|---|
Val 12 | Gly 12 | engineered mutation |
Ser 118 | Cys 118 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 19297.8 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 187.2 | |
All* | Total formula weight | 19485.0 |