8PI2
Native alpha-1-antitrypsin at 1.5 Angstrom (Cys232Ser)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Alpha-1-antitrypsin | polymer | 404 | 45595.7 | 1 | UniProt (P01009) Pfam (PF00079) | Homo sapiens (human) | Alpha-1 protease inhibitor,Alpha-1-antiproteinase,Serpin A1 |
| 2 | B (A) | GLYCINE | non-polymer | 75.1 | 1 | Chemie (GLY) | |||
| 3 | C (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 4 | D (A) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
| 5 | E (A) | water | water | 18.0 | 325 | Chemie (HOH) |
Sequence modifications
A: 2 - 394 (UniProt: P01009)
| PDB | External Database | Details |
|---|---|---|
| Met -9 | - | initiating methionine |
| Arg -8 | - | expression tag |
| Gly -7 | - | expression tag |
| Ser -6 | - | expression tag |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| His -1 | - | expression tag |
| His 0 | - | expression tag |
| Thr 1 | - | expression tag |
| Ser 232 | Cys 256 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 45595.7 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 215.3 | |
| All* | Total formula weight | 45810.9 |
