8PI0
NMR2 Structure of KRAS G12V (GMPPNP bound) in complex with 5-(1H-indol-2-l)piperazin-2-one
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA_b | polymer | 168 | 19168.6 | 1 | UniProt (A0A024RAV5) In PDB | Homo sapiens (human) | |
2 | A | (5~{S})-5-(1~{H}-indol-2-yl)piperazin-2-one | non-polymer | 215.3 | 1 | Chemie (YVW) |
Sequence modifications
A: 1 - 168 (UniProt: A0A024RAV5)
PDB | External Database | Details |
---|---|---|
Val 12 | Gly 12 | engineered mutation |
Ser 118 | Cys 118 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 19168.6 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 215.3 | |
All* | Total formula weight | 19383.8 |