8PFE

Crystal Structure of an Hexavariant of the b1 Domain of Human Neuropilin-1 in Complex with the KDKPPR Peptide

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C	Neuropilin-1	polymer	180	20295.0	2	UniProt (O14786) Pfam (PF00754) In PDB	Homo sapiens (human)	Vascular endothelial cell growth factor 165 receptor
2	B, D	LYS-ASP-LYS-PRO-PRO-ARG	polymer	6	742.9	2		unidentified
3	A	ACETATE ION	non-polymer		59.0	1	Chemie (ACT)
4		water	water		18.0	377	Chemie (HOH)

Sequence modifications

A, C: 273 - 427 (UniProt: O14786)

PDB	External Database	Details
Met 248	-	initiating methionine
Gly 249	-	expression tag
Ser 250	-	expression tag
Ser 251	-	expression tag
His 252	-	expression tag
His 253	-	expression tag
His 254	-	expression tag
His 255	-	expression tag
His 256	-	expression tag
His 257	-	expression tag
Gly 258	-	expression tag
Ser 259	-	expression tag
Gly 260	-	expression tag
Ser 261	-	expression tag
Gly 262	-	expression tag
Leu 263	-	expression tag
Glu 264	-	expression tag
Val 265	-	expression tag
Leu 266	-	expression tag
Phe 267	-	expression tag
Gln 268	-	expression tag
Gly 269	-	expression tag
Pro 270	-	expression tag
His 271	-	expression tag
Met 272	-	expression tag
Lys 277	Glu 277	engineered mutation
Lys 285	Glu 285	engineered mutation
Lys 289	Asp 289	engineered mutation
Lys 367	Glu 367	engineered mutation
Glu 373	Lys 373	engineered mutation
Glu 397	Lys 397	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	42075.8
Non-Polymers*	Number of molecules	1
	Total formula weight	59.0
All*	Total formula weight	42134.9

*Water molecules are not included.