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8PEO

H3K36me2 nucleosome-LEDGF/p75 PWWP domain complex

Replaces:  7PH5
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, EHistone H3polymer13515271.92UniProt (A0A310TTQ1)
Pfam (PF00125)
UniProt (by SIFTS) (P84233)
In PDB
Xenopus laevis (African clawed frog)
2B, FHistone H4polymer10211263.22UniProt (P62799)
Pfam (PF15511)
In PDB
Xenopus laevis (African clawed frog)
3C, GHistone H2Apolymer12913978.22UniProt (Q6AZJ8)
Pfam (PF00125)
Pfam (PF16211)
UniProt (by SIFTS) (P06897)
In PDB
Xenopus laevis (African clawed frog)
4D, HHistone H2B 1.1polymer12213524.82UniProt (P02281)
Pfam (PF00125)
In PDB
Xenopus laevis (African clawed frog)H2B1.1
5IWidom 601 DNA (147-MER)polymer14745138.81synthetic construct
6KPC4 and SFRS1-interacting proteinpolymer53060224.51UniProt (O75475)
Pfam (PF00855)
Pfam (PF11467)
In PDB
Homo sapiens (human)CLL-associated antigen KW-7,Dense fine speckles 70 kDa protein,DFS 70,Lens epithelium-derived growth factor,Transcriptional coactivator p75/p52
7JWidom 601 DNA (147-MER)polymer14745610.01synthetic construct
8A(2R)-2-amino-3-(2-dimethylaminoethylsulfanyl)propanoic acidnon-polymer192.31Chemie (M2L)
Sequence modifications
A, E: 1 - 135 (UniProt: A0A310TTQ1)
PDBExternal DatabaseDetails
Ala 110Cys 111conflict
D, H: 1 - 122 (UniProt: P02281)
PDBExternal DatabaseDetails
Thr 29Ser 33conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains11
Total formula weight259049.4
Non-Polymers*Number of molecules1
Total formula weight192.3
All*Total formula weight259241.7
*Water molecules are not included.

222036

PDB entries from 2024-07-03

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