8PBT
Mutant K1482M of the dihydroorotase domain of human CAD protein bound to the substrate dihydroorotate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | CAD protein | polymer | 362 | 39696.4 | 1 | UniProt (P27708) Pfam (PF01979) | Homo sapiens (human) | |
| 2 | B (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 3 | C (A) | (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID | non-polymer | 158.1 | 1 | Chemie (DOR) | |||
| 4 | D, E, F, G, H... (A) | ZINC ION | non-polymer | 65.4 | 7 | Chemie (ZN) | |||
| 5 | K, L, M, N, O... (A) | FORMIC ACID | non-polymer | 46.0 | 12 | Chemie (FMT) | |||
| 6 | W (A) | water | water | 18.0 | 330 | Chemie (HOH) |
Sequence modifications
A: 1460 - 1821 (UniProt: P27708)
| PDB | External Database | Details |
|---|---|---|
| Met 1482 | Lys 1482 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 39696.4 | |
| Non-Polymers* | Number of molecules | 21 |
| Total formula weight | 1260.4 | |
| All* | Total formula weight | 40956.8 |
